Community Oncology Connections™: Advancing Precision Testing and HER2-Targeted Care for Gastroesophageal Adenocarcinoma – Minnesota

Activity Overview

The management of esophagogastric adenocarcinoma has evolved substantially with the introduction of effective targeted and immunologic therapies. However, these therapies are appropriate mainly for patients with specific biomarkers, necessitating careful coordination among the multidisciplinary team to ensure proper tissue stewardship and testing, which, in turn, allows for appropriate treatment selection and sequencing, as well as the management and mitigation of adverse events (AEs).

In this series of live, virtual webcasts, experts in the management of esophagogastric adenocarcinoma discuss the evaluation and treatment of HER2-positive disease across the treatment continuum. Each program in the series addresses distinct clinical challenges, from first-line treatment selection through management of progression and AEs associated with HER2-directed therapies. These points are discussed in the context of patient case scenarios that reflect the decisions clinicians encounter in practice.

This educational activity is an archive of the live presentation held on August 6, 2026.

Target Audience

This educational program is primarily directed toward medical oncologists, molecular pathologists, radiologists, gastroenterologists, advanced practice providers, and nurses who are involved in the management of patients with advanced or metastatic gastroesophageal (GEA) cancers.

Learning Objectives

Upon successful completion of this activity, you should be better prepared to:

• Apply best practices for HER2 biomarker testing in patients with GEA to guide timely, individualized treatment decisions
• Evaluate emerging clinical trial data assessing novel HER2-targeted treatment strategies for GEA
• Incorporate the latest evidence on HER2-directed therapies into individualized treatment plans for patients with advanced GEA
• Implement strategies to mitigate and manage AEs associated with HER2-targeted therapy

The staff of Physicians’ Education Resource^®, LLC have no relevant financial relationships with ineligible companies.

PER^® mitigated all conflicts of interest for faculty, staff, and planners prior to the start of this activity by using a multistep process.

Off-Label Disclosure and Disclaimer

This accredited continuing education activity was planned in accordance with the ACCME Standards for Integrity and Independence to ensure balance, objectivity, independence, and scientific rigor. Faculty were instructed to use generic names when possible and to base recommendations on the best available evidence. Proprietary product names may be referenced in clinical discussion for educational purposes only and do not imply endorsement.

This activity may include discussion of investigational, unapproved, or off‑label uses of drugs or devices. Learners are advised to consult prescribing information for products discussed. Content is provided for educational purposes only and is not a substitute for the independent clinical judgment of a health care professional. Learners are encouraged to critically evaluate the information presented and apply their own clinical judgment.

The views expressed are those of the individual faculty members and do not necessarily reflect the views of the accredited provider or any entity providing commercial support.

This activity may have used AI-assisted tools to support educational development. All content was reviewed and approved by qualified faculty or planners. The accredited provider retains full responsibility for accuracy, balance, and independence.