Activity Overview
Non–muscle-invasive bladder cancer (NMIBC) represents the majority of newly-diagnosed bladder cancers, and it remains associated with high rates of recurrence and progression despite standard therapies. Management is increasingly complex due to ongoing shortages of Bacillus Calmette-Guerin vaccine, limited durability of conventional intravesical treatments, and the rapid emergence of novel immunotherapies, gene therapies, and advanced drug-delivery platforms. Clinicians continue to face challenges in risk stratification, treatment sequencing, and integrating newly approved and investigational agents into personalized care plans.
This continuing medical education–certified program is delivered using the Medical Crossfire® format, which leverages expert debate and multidisciplinary discussion to translate emerging clinical data into practical, real-world decision-making. The virtual format enables broad participation by urologists, medical oncologists, and advanced practice providers and facilitates timely education and interactive exchange on evolving NMIBC treatment strategies without geographic barriers.
This educational activity is an archive of the live virtual symposium held on February 23, 2026.
Target Audience
This educational program is directed toward medical oncologists, urologists, radiologists, and other physicians who are interested in the treatment of NMIBC.
Learning Objectives
Upon successful completion of this activity, you should be better prepared to:
- Implement best practices for the accurate diagnosis and risk stratification of non–muscle-invasive bladder cancer (NMIBC)
- Describe the mechanisms of action and supporting clinical trial data for recently approved and emerging therapies in NMIBC
- Integrate novel therapies into personalized care plans for patients with NMIBC
- Apply multidisciplinary care strategies to optimize outcomes in patients with NMIBC, including management of treatment-related adverse events and effective coordination of care

Ashish M. Kamat, MD, MBBS
Professor (Tenured) of Urologic Oncology
Wayne B. Duddlesten Sr Professorship in Cancer Research
Director, Bladder Cancer Research
President, International Bladder Cancer Group
The University of Texas MD Anderson Cancer Center
Houston, TX
Disclosures: Advisor, Consultant, Speaker, Honoraria Recipient: Astellas Pharma, Atonco Pharma, Biological Dynamics, Bristol Myers Squibb, CG Oncology, Cystotech, Eisai, EnGene, Ferring, Genentech, Imagin Medical, ImmunityBio, Imvax, Incyte, Janssen, Medac, Merck, Nonagen Bioscience, Pfizer, Photocure, Protara Therapeutics, Roche, Seagen, Sesen Bio (now Carisma), Theralase, UroGen Pharma, US Biotest, Valar Labs, Vivet Therapeutics; Grant/Research Funding: Arquer Diagnostics, EnGene, FKD Therapies (now Ferring), Patient-Centered Outcomes Research Institute, Photocure, Seagen, SWOG; Joint Patent With The University of Texas MD Anderson Cancer Center: CyPRIT (Cytokine Predictors of Response to Intravesical Therapy); Leadership/Fiduciary Role: American Urological Association, European Urology Oncology, International Bladder Cancer Group, Journal of Urology, UroToday, World Bladder Cancer Patient Coalition

Katie S. Murray, DO, MS
Professor, Department of Urology
NYU Grossman School of Medicine
Chief, Urology Service
Bellevue Hospital Center
New York, NY
Disclosures: Advisor, Consultant, Speaker, Honoraria Recipient: Curium, Ferring Pharmaceuticals, Relmada, UroGen Pharma

Thomas Powles, MD, MBBS, MRCP
Professor of Genitourinary Oncology
Director and Lead for Solid Tumour Research
Barts Cancer Centre at St Bartholomew’s Hospital
London, UK
Disclosures: Advisor, Consultant, Speaker, Honoraria Recipient: AstraZeneca, Bristol Myers Squibb, Exelixis, Incyte, Ipsen, Merck Sharp & Dohme, Novartis, Pfizer; Grant/Research Funding: AstraZeneca, Bristol Myers Squibb, Exelixis, Ipsen, Merck Sharp & Dohme, Novartis, Pfizer, Roche, Seattle Genetics
The staff of Physicians’ Education Resource®, LLC have no relevant financial relationships with ineligible companies.
PER® mitigated all COI for faculty, staff, and planners prior to the start of this activity by using a multistep process.
Off-Label Disclosure and Disclaimer
This activity may or may not discuss investigational, unapproved, or off-label use of drugs. Learners are advised to consult prescribing information for any products discussed. The information provided in this accredited activity is for continuing education purposes only and is not meant to substitute for the independent clinical judgment of a health care professional relative to diagnostic, treatment, or management options for a specific patient’s medical condition. The opinions expressed in the content are solely those of the individual faculty members and do not reflect those of PER® or any company that provided commercial support for this activity.

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