Overview:
Advancements in molecular testing and targeted therapies are transforming the management of advanced non-small cell lung cancer (NSCLC). This certified medical education (CME) activity brings together leading experts to provide a practical, case-based approach to understanding and applying the latest clinical evidence to optimize patient care. Participants will gain insights into the nuances of molecular profiling, the integration of tissue- and liquid-based testing, and the application of NCCN guideline recommendations for oncogenic drivers.
The interactive format includes case-based discussions highlighting challenges such as treatment resistance, biomarker selection for immunotherapy, and the integration of multidisciplinary strategies. Case discussions will also explore the role of emerging therapies to treat a patient with resistance to EGFR TKI therapy, implementing therapy for patients with a KRAS mutation and interpreting and acting on molecular testing that reveals RET-rearranged disease.
Learning Objectives:
Upon completion of this activity, participants will be able to:
- Assess current biomarkers and molecular tests that support personalization of therapy in advanced NSCLC
- Evaluate efficacy and safety results from clinical trials investigating novel approaches for the management of patients with advanced NSCLC
- Apply evidence-based precision diagnostic approaches to individualized treatment plans for patients with NSCLC Integrate best practices regarding the prevention, mitigation, and management of treatment-related adverse events

Stephen Liu, MD

Ignacio Wistuba, MD

Helena Yu, MD

Michelle Afkahmi, MD
Physicians’ Education Resource®, LLC, is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.
Physicians’ Education Resource®, LLC, designates this live activity for a maximum of 1.5 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Physicians’ Education Resource®, LLC, is approved by the California Board of Registered Nursing, Provider #16669, for 1.5 Contact Hours.

