Rapid Reviews in Retina™: 2026 Bimonthly Updates: Part 4 – DME

Activity Overview

Next-generation anti-VEGF therapies that provide opportunities for longer intervals between injections are indicated for the treatment of diabetic macular edema (DME). In this fourth episode of a 6-part series, an expert faculty member shares clinical trial and real-world data and personal perspectives on individualizing the treatment of patients with DME using these options.

Target Audience

This educational curriculum is directed toward retina specialists and ophthalmologists.

Learning Objectives

Upon successful completion of this activity, you should be better prepared to:

• Summarize the clinical evidence supporting next-generation anti-VEGF therapy for treatment-naïve and previously treated DME
• Evaluate anatomic and functional outcomes to guide dosing interval decisions in DME management
• Develop patient communication strategies that set appropriate expectations for treatment durability and visual outcomes

The staff of Physicians’ Education Resource^®, LLC have no relevant financial relationships with ineligible companies.

PER^® mitigated all conflicts of interest for faculty, staff, and planners prior to the start of this activity by using a multistep process.

Off-Label Disclosure and Disclaimer

This accredited continuing education activity was planned in accordance with the ACCME Standards for Integrity and Independence to ensure balance, objectivity, independence, and scientific rigor. Faculty were instructed to use generic names when possible and to base recommendations on the best available evidence. Proprietary product names may be referenced in clinical discussion for educational purposes only and do not imply endorsement.

This activity may include discussion of investigational, unapproved, or off‑label uses of drugs or devices. Learners are advised to consult prescribing information for products discussed. Content is provided for educational purposes only and is not a substitute for the independent clinical judgment of a health care professional. Learners are encouraged to critically evaluate the information presented and apply their own clinical judgment.

The views expressed are those of the individual faculty members and do not necessarily reflect the views of the accredited provider or any entity providing commercial support.

This activity may have used AI-assisted tools to support educational development. All content was reviewed and approved by qualified faculty or planners. The accredited provider retains full responsibility for accuracy, balance, and independence.