Activity Overview
Next-generation anti-VEGF therapies that provide opportunities for longer injection intervals are indicated for the treatment of macular edema following retinal vein occlusion (RVO). In this third episode of a 6-part series, an expert faculty member shares clinical trial data and personal perspectives on individualizing patient treatment with these options.
Target Audience
This educational curriculum is directed toward retina specialists and ophthalmologists.
Learning Objectives
Upon successful completion of this activity, you should be better prepared to:
- Differentiate the treatment considerations for macular edema secondary to branch RVO (BRVO) vs central RVO (CRVO) when using next-generation anti-VEGF therapy
- Apply interval extension strategies that balance edema control with reduced treatment burden in RVO patients
- Recognize patterns of edema recurrence and implement timely retreatment protocols to prevent vision loss

Sharon Fekrat, MD
Academic Vitreoretinal Surgeon
Duke Eye Center, Duke Health Integrated Practice
Durham, NC
Disclosures: Advisor, Consultant, Fee-for-Service-Recipient: 4DMT, Alcon, Amgen, Apellis, Astellas, Bausch Surgical, Conexiant, DRCR Retina Network Data and Safety Monitoring Committee, Evolve Med Education, Harrow, Regeneron, Teladoc, YoungMD Connect; Grant/Research Funding: Genentech, Optos; Royalty or Patient Benefits: Alcon, Slack, Wolters Kluwer
The staff of Physicians’ Education Resource®, LLC have no relevant financial relationships with ineligible companies.
PER® mitigated all conflicts of interest for faculty, staff, and planners prior to the start of this activity by using a multistep process.
Off-Label Disclosure and Disclaimer
This accredited continuing education activity was planned in accordance with the ACCME Standards for Integrity and Independence to ensure balance, objectivity, independence, and scientific rigor. Faculty were instructed to use generic names when possible and to base recommendations on the best available evidence. Proprietary product names may be referenced in clinical discussion for educational purposes only and do not imply endorsement.
This activity may include discussion of investigational, unapproved, or off‑label uses of drugs or devices. Learners are advised to consult prescribing information for products discussed. Content is provided for educational purposes only and is not a substitute for the independent clinical judgment of a health care professional. Learners are encouraged to critically evaluate the information presented and apply their own clinical judgment.
The views expressed are those of the individual faculty members and do not necessarily reflect the views of the accredited provider or any entity providing commercial support.
This activity may have used AI-assisted tools to support educational development. All content was reviewed and approved by qualified faculty or planners. The accredited provider retains full responsibility for accuracy, balance, and independence.

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