Overview:
Given the availability of highly efficacious treatments for NSCLC, it is more important than ever that patients with NSCLC undergo comprehensive testing to identify targetable alterations. In addition to detecting common mutations in lung cancer genes, such as EGFR, ALK, and KRAS, developments in molecular testing via tissue or liquid biopsy enable less frequent targetable mutations in NSCLC, including alterations and mutations in MET, ROS1, RET, HER2, and NTRK, to be revealed. Identification of these patients for approved targeted agents or clinical trial participation, however, requires rapid and reliable testing using the most appropriate assay.
This LIVE! Testing Board webcast will provide an in-depth review of current pathologic testing methodology aimed to improve the interpretation of NSCLC testing report results. This program will feature a case-based panel discussion of pathologic reports that identify potential actionable alterations matched to appropriate treatment selection for patients with NSCLC.
Learning objectives:
- Outline recent approaches for biomarker and mutational tests, including NGS and liquid biopsy tests, in patients with NSCLC
- Describe clinical trial evidence concerning the role of biomarker-directed therapies for patients with NSCLC in the context of clinical guidelines for management of advanced NSCLC
- Detail emerging biomarker-directed therapeutic targets and assessment strategies in advanced NSCLC
- Determine the importance of multidisciplinary management for the assessment and interpretation of molecular data in advanced NSCLC
Target Audience:
This educational program is directed toward the CAP audience, primarily pathologists and other healthcare professionals, involved in the diagnosis and treatment of NSCLC.

Ignacio I. Wistuba, MD

Charu Aggarwal, MD, MPH

Justin Gainor, MD

Lynette Sholl, MD
1:00 PM |
Welcome, Introductions, Pre-Session Survey |
|
15 min |
The Role of Biopsy and Testing Technology in NSCLC: Current Options |
Lynette Sholl |
10 min |
Trial Updates and Emerging Biomarkers in Advanced NSCLC |
Justin Gainor |
15 min |
Case #1: Patient with resected stage II NSCLC found to have an ALK rearrangement |
Justin Gainor |
15 min |
Case #2: Molecular Testing in a Patient with Acquired Resistance to EGFR TKI Therapy |
Charu Aggarwal |
15 min |
Case #3: Patient with malignant pleural effusion relatively uninformative plasma biopsy |
Lynette Sholl |
15 min |
Case #4: Never Smoker With NSCLC Has a Bone Biopsy; Decision Making Around Liquid Biopsy |
Justin Gainor |
15 min |
Case #5: Patient with ROS1-positive NSCLC |
Charu Aggarwal |
15 min |
Q&A Session and Post-Session Survey |
Faculty Panel |
Coming Soon!

