Overview:
Lambert-Eaton myasthenic syndrome (LEMS) is a rare, frequently under-recognized paraneoplastic neurologic disorder that may occur in patients with small cell lung cancer (SCLC). Overlapping features with myasthenia gravis, chemotherapy-induced neuropathy, or deconditioning often delay diagnosis, leading to significant morbidity, functional decline, and missed opportunities to identify SCLC earlier.
This interactive, hybrid satellite symposium will be presented in conjunction with the 2025 IASLC North America Conference on Lung Cancer in Chicago, Illinois. Using a case-based format, our expert faculty will highlight hallmark clinical clues, outline evidence-based diagnostic pathways, and provide strategies for optimizing care with available therapies and multidisciplinary coordination. By addressing real-world challenges in recognition and management, the session aims to equip clinicians with actionable tools to improve outcomes for patients with SCLC and LEMS.
Learning Objectives:
Upon completion of this activity, participants will be able to:
- Identify distinguishing clinical features of paraneoplastic LEMS that warrant further workup
- Apply a guideline-concordant diagnostic pathway for LEMS that incorporates findings from physical exam, electrodiagnostic studies, antibody testing, and imaging
- Initiate therapy for paraneoplastic LEMS with appropriate consideration for titration and monitoring
- Define best practices for multidisciplinary fast-track pathways with defined roles, referral SLAs, and EMG access targets
Millie Das, MD
Clinical Professor, Medicine - Oncology
Chief, Oncology
VA Palo Alto Health Care System
Stanford Cancer Institute
Palo Alto, CA
Wade Iams, MD, MSCI
Director of Lung Cancer Research
Greco Hainsworth Centers for Research
Tennessee Oncology
Nashville, TN
Ruham Nasany, MD
Director, In-patient Neuro Oncology Service
Assistant Professor, Department of Neurology
University of Miami Miller School of Medicine
Aventura, FL
Physicians’ Education Resource®, LLC, is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.
Physicians’ Education Resource®, LLC, designates this live activity for a maximum of 1.0 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Physicians’ Education Resource®, LLC is approved by the California Board of Registered Nursing, Provider #16669, for 1.0 Contact Hour.