Activity Overview
“D” Is for Diagnosis is an interactive, case-based program that challenges learners to think like clinical detectives as they work with expert faculty to evaluate a patient with recurrent acute abdominal pain. As the case unfolds, participants will analyze clinical clues, develop a differential diagnosis, and navigate common diagnostic pitfalls while considering both common and uncommon causes of abdominal pain. This innovative format promotes active learning and clinical reasoning in an engaging and informative environment.
Target Audience
This educational activity is directed toward hepatologists, gastroenterologists, hematologists, nurse practitioners, physician associates, and other health care professionals involved in the diagnosis of acute hepatic porphyria (AHP).
Learning Objectives
Upon successful completion of this activity, you should be better prepared to:
- Describe clinical presentations of patients with AHP
- Identify the differential diagnosis of AHP
- Apply current assessment strategies to accurately diagnose patients with AHP based on clinical presentation

Brendan McGuire, MD, MS
Professor
Medical Director
Liver Transplantation
Director
Liver Center
University of Alabama at Birmingham
Birmingham, AL
Disclosures: Grant/Research Funding: Alnylam Pharmaceuticals, DISC Medicine

Herbert Bonkovsky, MD
Professor Emeritus of Gastroenterology, Internal Medicine
Wake Forest University
Winston-Salem, NC
Disclosures: Herbert Bonkovsky, MD, has no relevant financial relationships with ineligible companies.
The staff of Physicians’ Education Resource®, LLC have no relevant financial relationships with ineligible companies.
PER® mitigated all conflicts of interest for faculty, staff, and planners prior to the start of this activity by using a multistep process.
Off-Label Disclosure and Disclaimer
This accredited continuing education activity was planned in accordance with the ACCME Standards for Integrity and Independence to ensure balance, objectivity, independence, and scientific rigor. Faculty were instructed to use generic names when possible and to base recommendations on the best available evidence. Proprietary product names may be referenced in clinical discussion for educational purposes only and do not imply endorsement.
This activity may include discussion of investigational, unapproved, or off‑label uses of drugs or devices. Learners are advised to consult prescribing information for products discussed. Content is provided for educational purposes only and is not a substitute for the independent clinical judgment of a health care professional. Learners are encouraged to critically evaluate the information presented and apply their own clinical judgment.
The views expressed are those of the individual faculty members and do not necessarily reflect the views of the accredited provider or any entity providing commercial support.
This activity may have used AI-assisted tools to support educational development. All content was reviewed and approved by qualified faculty or planners. The accredited provider retains full responsibility for accuracy, balance, and independence.

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