Activity Overview
This Community Practice Connection™ activity provides an in-depth review of some highlights from the 2026 Community Oncology Connections™: Bridging Academic and Community Connections to Advance Precision and Targeted Care in Neurofibromatosis Type 1 Plexiform Neurofibromas program. This unique and engaging multimedia activity is ideal for community-based clinicians and focuses on the practical aspects of managing patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), helping clinicians to gain confidence in managing this complex disease. The program is designed for those who did not attend the live meeting and to help reinforce learning for those who did.
Target Audience
This educational program is primarily directed toward community-based oncologists, nurses, nurse practitioners/advanced practice providers, and other health care professionals involved in the treatment of NF1-PNs.
Learning Objectives
Upon successful completion of this activity, you should be better prepared to:
- Apply guideline-based diagnostic criteria to improve accurate identification, classification, and referral of patients with NF1-PNs
- Evaluate emerging clinical trial data on targeted therapies, including MEK inhibitors, to inform evidence-based treatment selection for patients with NF1-PNs
- Integrate patient-specific factors to develop individualized management plans for patients with NF1-PNs
- Identify, monitor, and manage adverse events associated with targeted therapies for NF1-PNs within real-world practice settings

Amy E. Armstrong, MD
Associate Professor of Pediatrics
Director, Solid Tumor Team
Codirector, Adolescent and Young Adult Sarcoma Program
Division of Pediatric Hematology/Oncology
Washington University in St Louis
St. Louis, MO
Disclosures: Advisor, Consultant, Fee-for-Service Recipient: SpringWorks; Speaker at Academic Conference: Alexion

Daniela A. Bota, MD, PhD
Professor, Neurology
Director, UCI Alpha Clinic
Medical Director, Comprehensive Brain Tumor Program
University of California, Irvine
Irvine, CA
Disclosures: Daniela A. Bota, MD, PhD, has no relevant financial relationships with ineligible companies.
The staff of Physicians’ Education Resource®, LLC have no relevant financial relationships with ineligible companies.
PER® mitigated all conflicts of interest for faculty, staff, and planners prior to the start of this activity by using a multistep process.
Off-Label Disclosure and Disclaimer
This accredited continuing education activity was planned in accordance with the ACCME Standards for Integrity and Independence to ensure balance, objectivity, independence, and scientific rigor. Faculty were instructed to use generic names when possible and to base recommendations on the best available evidence. Proprietary product names may be referenced in clinical discussion for educational purposes only and do not imply endorsement.
This activity may include discussion of investigational, unapproved, or off‑label uses of drugs or devices. Learners are advised to consult prescribing information for products discussed. Content is provided for educational purposes only and is not a substitute for the independent clinical judgment of a health care professional. Learners are encouraged to critically evaluate the information presented and apply their own clinical judgment.
The views expressed are those of the individual faculty members and do not necessarily reflect the views of the accredited provider or any entity providing commercial support.
This activity may have used AI-assisted tools to support educational development. All content was reviewed and approved by qualified faculty or planners. The accredited provider retains full responsibility for accuracy, balance, and independence.

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