Activity Overview
PD-L1 status and antibody-drug conjugates (ADCs) now anchor frontline treatment selection in metastatic triple-negative breast cancer (mTNBC). Still, community oncologists face variability in PD-L1 assay choice and scoring thresholds, a rapidly expanding ADC evidence base spanning monotherapy and immunotherapy-combination strategies, and toxicity profiles that differ by agent. Applying this evidence in daily practice requires clinicians to interpret biomarker results correctly, weigh trial data against real-world patient factors, and coordinate with multidisciplinary colleagues on testing, treatment selection, and adverse event management.
This online, on-demand webinar brings together renowned experts in mTNBC. In this educational program, these experts discuss recent mTNBC clinical trial data, followed by case presentations and discussions in an interactive format tailored to community oncology practice. The program is designed to translate evolving clinical evidence into practical, real-world decision-making and support personalized care for patients with mTNBC.
This educational activity is an archive of the live presentation held on September 18, 2026.
Target Audience
This educational program is primarily directed toward community-based oncologists, nurses, nurse practitioners/advanced practice providers, and other health care professionals involved in the treatment of TNBC.
Learning Objectives
Upon successful completion of this activity, you should be better prepared to:
- Describe how PD-L1 testing impacts treatment planning and regimen selection in patients with newly diagnosed mTNBC
- Select appropriate frontline strategies for mTNBC based on PD-L1 status, immunotherapy eligibility, patient preferences, and evolving clinical evidence
- Apply practical approaches to toxicity management, patient communication, and workflow integration in community oncology settings

Sarah M. Tolaney, MD, MPH
Chief, Division of Breast Oncology
Dana-Farber Cancer Institute
Associate Professor of Medicine
Harvard Medical School
Boston, MA
Disclosures: Advisor, Consultant, Speaker, Honoraria Recipient: Aadi Bio, Artios Pharma, Arvinas, AstraZeneca, Aktis Oncology, Avenzo Therapeutics, Bayer, BeOne Therapeutics, Bicycle Therapeutics, BioNTech, Blueprint Medicines, Boehringer Ingelheim, Boundless Bio, Bristol Myers Squibb/SystImmune, Celcuity, Circle Pharma, Cullinan Oncology, Daiichi Sankyo, eFFECTOR, Eisai, Eli Lilly, Genentech/Roche, Gilead, Hengrui USA, Jazz Pharmaceuticals, Johnson & Johnson/Ambrx/Mersana, Launch Therapeutics, Menarini/Stemline, Merck, Natera, Novartis, Olema, Pfizer/Seagen, Reveal Genomics, Samsung Bioepis, Sumitovant Biopharma, Summit Therapeutics, Tango Therapeutics, Tempus, Zuellig Pharma; Grant/Research Funding: AstraZeneca, Bristol Myers Squibb, Daiichi Sankyo, Exelixis, Genentech/Roche, Gilead, Jazz Pharma, Lilly, Merck, Menarini/ Stemline, NanoString Technologies, Novartis, OncoPep, Pfizer/Seagen

Yelda Nouri, MD
Attending Physician
Medical Oncology/Hematology
New York Cancer & Blood Specialists
New York, NY
Disclosures: Advisor, Consultant, Speaker, Honoraria Recipient: AstraZeneca, Daiichi Sankyo; Speakers Bureau: AstraZeneca, Daiichi Sankyo
The staff of Physicians’ Education Resource®, LLC (PER®) have no relevant financial relationships with ineligible companies.
PER mitigated all COI for faculty, staff, and planners before the start of this activity.
Off-Label Disclosure and Disclaimer
This activity may or may not discuss investigational, unapproved, or off-label use of drugs. Learners are advised to consult prescribing information for any products discussed. The information provided in this accredited activity is for continuing education purposes only and is not meant to substitute for the independent clinical judgment of a health care professional relative to diagnostic, treatment, or management options for a specific patient’s medical condition. The opinions expressed in the content are solely those of the individual faculty members and do not reflect those of PER or any company that provided commercial support for this activity.

GET STARTED WITH THIS PROGRAM:
Register now to gain access to this program.
Create AccountAlready Registered? Login Here