Overview:
Castleman disease (CD) is a rare group of lymphoproliferative disorders that can be difficult to recognize and classify due to symptoms that overlap with lymphoma, autoimmune diseases, and infections. As a result, diagnostic delays are common, and uncertainty remains regarding optimal treatment selection, particularly for multicentric forms of the disease.
This Cases and Conversations
virtual webcast will use interactive patient cases and expert discussion to
address key challenges in the diagnosis and management of CD. Faculty will
review current evidence and guideline-based approaches for unicentric CD, HHV-8–associated
multicentric CD, and idiopathic multicentric CD, with the goal of improving
clinician confidence and patient care.
Learning Objectives:
Upon completion of this activity, participants will be able to:
- Recognize the clinical, laboratory, and pathologic features that should prompt consideration of CD
- Differentiate unicentric CD from multicentric subtypes, including HHV-8–associated and iMCD, using appropriate diagnostic testing and clinical context
- Apply evidence-based and guideline-recommended treatment strategies for CD based on subtype, severity, and response to initial therapy
Target Audience:
This educational activity is directed toward physicians, hematologists, pathologists, dermatologists, nurses, NPs/PAs, pharmacists, and other HCPs involved in the diagnosis and treatment of hematological disorders.
Matthew Lunning, DO, FACP
Professor & James O. Armitage, MD, Chair of Hematologic Malignancies
Interim Chief of Hematology
Medical Director, Gene & Cellular Therapy
Assistant Vice Chancellor for Clinical Research
Fred & Pamela Buffett Cancer Center
University of Nebraska Medical Center
Omaha, NE
Frits van Rhee, MD, PhD, MRCP(UK), FRCPath
Professor of Medicine
Clinical Director Myeloma Center
Associate Director Clinical Sciences of the Winthrop P. Rockefeller Cancer Institute
Charles and Clyde Scharlau Chair for Hematologic Malignancies Research
University of Arkansas for Medical Sciences
Little Rock, AR
Sudipto Mukherjee, MD, PhD, MPH
Clinical Assistant Professor, Department of Medicine
Member, Immune Oncology Program, Case Comprehensive Cancer Center
Case Western Reserve University
Physician, Department of Hematology and Medical Oncology
Cleveland Clinic Cancer Center
Cleveland, OH
Physicians’ Education Resource®, LLC, is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.
Physicians’ Education Resource®, LLC designates this live activity for a maximum of 1.0 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Physicians’
Education Resource®, LLC is approved by the California Board of
Registered Nursing, Provider #16669, for 1.0 Contact Hour.
Physicians Education Resource®, LLC is accredited by the Accreditation Council for Pharmacy Education (ACPE) as a provider of continuing pharmacy education. This knowledge-based activity is approved for a maximum of 1.0 contact hour (1.0 CEU) under several UAN numbers.
