BURST CME™: The Evolving Role of PD-1 Inhibition in Nasopharyngeal Carcinoma Management

Release Date: August 29, 2024

Expiration Date: August 29, 2025

Activity Overview

The close association between Epstein-Barr virus (EBV) infection and the upregulation of PD-1 in nasopharyngeal carcinoma (NPC) cells suggests a role for PD-1 inhibition in patients with no radiotherapy option. Combinations of anti–PD-1 agents and chemotherapy as well as adoptive cell immunotherapy are under investigation in managing advanced NPC.

This educational activity is designed to provide participants with an overview of recent advances in immunotherapy strategies in NPC. The written material is supplemented by video clips from an expert in the treatment of these tumors to provide additional context and insight.

Target Audience

This educational activity is directed toward physicians, pathologists, nurses, pharmacists, and other health care practitioners interested in NPC.

Learning Objectives

Upon successful completion of this activity, you should be better prepared to:

• Evaluate the significance of NPC pathophysiology and the influence of EBV on tumor behavior and subsequent predictive markers and EBV DNA levels to enhance decision-making in treatment strategies
• Assess the current PD-1 inhibition clinical trial data and the role of these emerging therapies into a patient care plan.

Faculty, Staff, and Planners’ Disclosures

The staff of Physicians’ Education Resource^®, LLC, have no relevant financial relationships with ineligible companies.

PER^® mitigated all COI for faculty, staff, and planners prior to the start of this activity by using a multistep process.

Off-Label Disclosure and Disclaimer

This activity may or may not discuss investigational, unapproved, or off-label use of drugs. Learners are advised to consult prescribing information for any products discussed. The information provided in this accredited activity is for continuing education purposes only and is not meant to substitute for the independent clinical judgment of a health care professional relative to diagnostic, treatment, or management options for a specific patient’s medical condition. The opinions expressed in the content are solely those of the individual faculty members and do not reflect those of PER^® or any company that provided commercial support for this activity.