. Dr. Kenneth L. McClain goes further in depth on HLH by discussing CNS HLH, malignancy HLH, and EBV monitoring in conjunction with HLH. These scenarios become complicated because the treatment of HLH often coincides with the additional concern presented. A CNS evaluation and EBV monitoring are useful tools in identifying HLH, however the HLH treatment method may not be affective in treating the later concern. By providing CME on diseases like HLH, physicians can access information on rare diseases that is often presented exclusively through articles.