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Working Group™: Strategies for Recognizing and Taking Steps to Address Disparities in Cancer Care Among Diverse Populations
Sunday, June 5, 2022
Hilton Chicago | Continental C
Registration & Dinner: 6:30 pm – 7:00 pm CDT
Scientific Session: 7:00 pm – 9:00 pm CDT
Learning Objectives
- Explain disparities in cancer outcomes and care among diverse patient populations;
- Evaluate strategies to broaden oncology clinical trial opportunities and enrollment among diverse populations;
- Analyze gaps in the screening, diagnosis, treatment selection, and access to care in diverse populations with cancer;
- Identify strategies to overcome disparities in diagnosis, testing, and treatment for patients with cancer.

Medical Crossfire®: Multidisciplinary Discussions on the Application of Novel EGFR exon 20 Targeted Regimens for NSCLC Management
Sunday, June 5, 2022
Hilton Chicago | Continental A
Registration & Dinner: 6:30 pm – 7:00 pm CDT
Scientific Session: 7:00 pm – 9:00 pm CDT
Learning Objectives
- Assess optimal molecular testing strategies for patients with NSCLC and EGFR exon 20 insertions along the continuum of care
- Describe the role of multidisciplinary team members in the delivery of care for patients with NSCLC and EGFR exon 20 insertions
- Apply safety and efficacy results from clinical trials assessing targeted approaches for the management of patients with advanced NSCLC and EGFR exon 20 insertions
- Summarize approaches to mitigate and manage treatment-related adverse events associated with the use of targeted therapy in patients with NSCLC and EGFR exon 20 insertions

Placing New MPN Therapies into Context Through Illustrated Case Discussions
Sunday, June 5, 2022
Hilton Chicago | Continental B
Registration & Dinner: 6:30 pm – 7:00 pm CDT
Scientific Session: 7:00 pm – 9:00 pm CDT
Learning Objectives
- Determine factors that inform care plans for patients with MF and PV based on genetics, risk stratification, and symptom burden
- Explain the mechanistic rationale for the application of therapeutic approaches for the management of MPNs
- Describe evidence from investigations on treatment approaches for MF and PV, including how these findings can inform proactive strategies planning to manage treatment-related toxicities
- Devise strategies to integrate emerging evidence to manage clinical scenarios commonly encountered in the care of patients with MPNs along the disease continuum

Medical Crossfire®: Leveraging EGFR Mutation Profiles to Personalize Therapeutic Decisions in Resected and Metastatic NSCLC Settings
Friday, June 3, 2022
Hyatt Regency | Plaza Ballroom
Registration and Dinner: 6:00 - 6:30 PM CDT
Scientific Session: 6:30 PM - 8:30 PM CDT
Learning Objectives
- Discuss the role of multidisciplinary team members in addressing barriers to testing and the interpretation of molecular test results for patients with early stage and metastatic NSCLC
- Summarize high-risk genomic co-mutations that occur in patients with EGFR mutation–positive NSCLC
- Assess outcomes among EGFR mutation profiles with the application of different EGFR inhibitor-based monotherapy and combination regimens
- Apply approaches to mitigate and manage treatment-related toxicities associated with the use of targeted therapy in patients with early-stage and metastatic NSCLC
Top 10 Oncogenic Markers in NSCLC for 2022: Evolution of Tumor Testing Technologies, Novel Treatments, and Trials!
Friday, June 3, 2022
Hilton Chicago | Continental A
Registration & Dinner: 6:30 pm – 7:00 pm CDT
Scientific Session: 7:00 pm – 9:00 pm CDT
Learning Objectives
- Determine actionable biomarkers to inform decision-making in the management of advanced NSCLC
- Explain the role of testing and ways to facilitate diagnosis for NSCLC treatment
- Describe efficacy and safety of investigations that used actionable biomarkers to personalize NSCLC care
- Evaluate emerging targets and biomarker-driven strategies undergoing late-stage evaluation for use in advanced NSCLC

Hot Seat™: Expert Considerations to Maximize the Clinical Benefits of Targeted Therapies in Patients with Relapsed/Refractory DLBCL
Friday, June 3, 2022
Hilton Chicago | Continental B
Registration & Dinner: 6:30 pm – 7:00 pm CDT
Scientific Session: 7:00 pm – 9:00 pm CDT
Learning Objectives
- Determine DLBCL subtypes, biomarkers, and risk assessment methods, and how these factors inform treatment strategies for patients with relapsed/refractory (R/R) disease
- Evaluate the clinical profiles of current and emerging targeted therapies investigated for the treatment of R/R DLBCL
- Implement strategies to monitor and mitigate the impact of adverse events associated with targeted therapies among patients with R/R DLBCL
- Translate treatment guidelines and landmark trial data on targeted therapies to personalize sequencing strategies for patients with R/R DLBCL

Medical Crossfire®: Addressing the Top 10 Clinical Challenges in Melanoma
Friday, June 3, 2022
Hilton Chicago | International Ballroom South
Registration & Dinner: 6:30 pm – 7:00 pm CDT
Scientific Session: 7:00 pm – 9:00 pm CDT
Learning Objectives
- Assess recent clinical trial evidence concerning the safety and efficacy of immunotherapy used as single-agents or combination strategies for melanoma management
- Evaluate the efficacy and safety of targeted therapies, including BRAF/MEK inhibition, in the management of melanoma
- Describe treatment-related adverse events and appropriate management strategies for patients with melanoma
- Utilize approaches to optimize clinical decision-making across multiple lines of care in melanoma

Medical Crossfire®: How Are We Personalizing Integration of ICIs and Targeted Therapies to Optimize Outcomes in Endometrial Cancer?
Friday, June 3, 2022
Hilton Chicago | Continental C
Registration & Dinner: 6:30 pm – 7:00 pm CDT
Scientific Session: 7:00 pm – 9:00 pm CDT
Learning Objectives
- Evaluate the rationale for using genetic testing strategies in managing endometrial cancer through biomarker-based decision-making
- Summarize key results of clinical trials involving emerging treatments and combinations of therapy in patients with endometrial cancer, as guided by biomarkers and genomic data
- Describe relevant supportive measures in timely detection and management of potential treatment-related adverse events with therapies for endometrial cancer
- Explain the most efficient uses of biomarker-based therapy along with other relevant evaluation strategies to formulate personalized treatment plans

Medical Crossfire®: Evaluating the Potential Role of Next-Generation Selective Estrogen Receptor Degraders in the ER+/HER2- Breast Cancer
Saturday, June 4, 2022
Hilton Chicago | Continental A
Registration & Dinner: 6:30 pm – 7:00 pm CDT
Scientific Session: 7:00 pm – 9:00 pm CDT
Learning Objectives
- Describe efficacy and safety data of next-generation SERD agents for the management of HR+/HER2- breast cancer
- Explain how patient and tumoral characteristics can be aligned with clinical trial evidence to inform decision-making in the management of HR+/HER2- breast cancer
- Apply recent trial evidence to manage case scenarios typically encountered in HR+/HER2- breast cancer care and in consideration of evolving treatment paradigms in the field
- Determine ongoing trials concerning SERDs that are intended to address clinical gaps in the field of HR+/HER2- breast cancer management

Medical Crossfire®: Analyzing the Evolving Role of Liquid Biopsies Across Cancer Care
Saturday, June 4, 2022
Hilton Chicago | Continental C
Registration & Dinner: 6:30 pm – 7:00 pm CDT
Scientific Session: 7:00 pm – 9:00 pm CDT
Learning Objectives:
- Outline key features of liquid biopsies and how they differ from conventional biopsies in the diagnosis and monitoring of cancer
- Explain evidence concerning the reliability of existing and emerging liquid biopsy technologies in cancer care
- Evaluate the relevance of multiple forms of liquid biopsy in the biomarker-driven management of multiple common and less common cancer types
- Summarize the latest evidence concerning the use of liquid biopsy and best practices for real-world applications of these tests

Reshaping Higher-Risk MDS Patient-Centered Care with Emergence of Novel Evidence and Clinical Trials
Saturday, June 4, 2022
Hilton Chicago | Continental B
Registration & Dinner: 6:30 pm – 7:00 pm CDT
Scientific Session: 7:00 pm – 9:00 pm CDT
Learning objectives:
- Explain the criteria for MDS diagnosis, as well as available tools for its classification and risk stratification
- Review endpoints utilized in recent clinical trials that have changed treatment of high-risk MDS
- Discuss unmet clinical needs in patients with high-risk MDS and the rationale for emerging therapies and combination strategies in patients with MDS
- Report the efficacy and safety profiles for current and emerging approaches for the care of patients with higher-risk MDS

How Guidelines and Recent Clinical Trial Data Inform the Modern-Day Treatment of Advanced Prostate Cancer
Saturday, June 4, 2022
Hilton Chicago | International Ballroom South
Registration & Dinner: 6:30 pm – 7:00 pm CDT
Scientific Session: 7:00 pm – 9:00 pm CDT
Learning Objectives
- Explain clinical trial data and evidence-based recommendations for the management of nonmetastatic and metastatic forms of CRPC
- Optimize sequencing of current therapies
- Assess trial evidence on novel approaches to CRPC and their impact on evolving treatment paradigms
- Monitor and manage treatment-associated toxicities