Medical Crossfire®: Why is PSMA so Effective? To Affinity and Beyond


Wednesday, February 15th, 2022
Registration and Dinner: 7:00 PM – 7:30 PM PT
Scientific Session: 7:30 PM – 9:00 PM PT

Learning Objectives

  • Describe unmet clinical needs in the management of prostate cancer in the context of novel PSMA-directed strategies in diagnosis and management of prostate cancer
  • Assess emerging clinical trial evidence on evolving PSMA-targeting strategies and its potential implications on evolving treatment paradigms in metastatic castration-resistant prostate cancer (mCRPC)
  • Determine effective approaches to integrate and sequence PSMA-targeting radioligand strategies into current clinical practice to manage patients with mCRPC
  • Discuss potential multidisciplinary strategies to recognize and manage toxicities associated with currently approved as well as emerging PSMA-directed therapies for mCRPC care

New Targets, New Treatments, and New Combinations for the Management of Advanced Prostate Cancer


Thursday, February 16, 2023
Intercontinental San Francisco | 3rd floor, Grand Ballroom

Registration and Dinner: 7:00 PM - 7:30 PM PT
Scientific Session: 7:30 PM - 9:00 PM PT

Learning Objectives

  • Describe the pathophysiological mechanisms underlying current/emerging therapeutic approaches for the treatment of patients with CRPC
  • Assess practice-changing evidence on evolving therapeutic strategies for patients with nonmetastatic and metastatic CRPC
  • Determine measures to monitor for and mitigate the impact on outcomes of treatment-related adverse events in CRPC care settings
  • Apply recent guidelines and evidence from pivotal trials to inform treatment decisions among patients with CRPC across lines of care

Medical Crossfire®: How Does the Evidence Inform Your RCC Sequence? The Experts Share Clinical Perspectives


Friday, February 17, 2023
Parc 55 San Francisco | Room: Cyril Magnin

Registration & Dinner: 6:30 PM - 7:00 PM PT
Scientific Session: 7:00 PM - 9:00 PM PT

Learning Objectives

  • Evaluate the mechanistic rationale for evaluating targeted therapies, immunotherapies, and combinations to manage RCCExplain clinical evidence for the management of GU malignancies across multiple lines of care
  • Assess the implications of recent trial data on novel therapies and combinations in the context of evolving treatment paradigms for high-risk, advanced/metastatic, and early-stage RCC
  • Determine effective strategies for the identification and management of treatment-related toxicities among patients who receive care for RCC
  • Devise personalized care plans for RCC by incorporating methods to stratify risk, clinical trial evidence, and patient- and tumor-specific characteristics

Expert Perspectives on Emerging CDK4/6 Inhibitor Strategies in Advanced Prostate Cancer Management Settings


Friday, February 17, 2023
W San Francisco | Great Room

Registration & Dinner: 7:00 PM - 7:30 PM PT
Scientific Session: 7:30 PM - 9:00 PM PT

Learning Objectives

  • Explain the pathophysiological mechanisms of CDK4/6 dysregulation in prostate cancer and rationale underlying their inhibition in advanced CSPC and CRPC
  • Assess study design and clinical updates on CDK4/6 inhibitors investigated for the treatment of patients with advanced CSPC and CRPC
  • Evaluate evidence from pivotal trials on CDK4/6 inhibitors within the context of evolving therapeutic strategies for patients with advanced prostate cancer
  • Develop proactive strategies to monitor and mitigate adverse events associated with CDK4/6 inhibitors evaluated in patients with prostate cancer