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Accreditation/Credit Designation

Physicians' Education Resource®, LLC is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education (CME) for physicians.

Physicians' Education Resource®, LLC, designates this enduring material for a maximum of 2.0 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Physicians' Education Resource®, LLC, is approved by the California Board of Registered Nursing, Provider #16669, for 2.0 Contact Hours.

Hematology Briefings™: The Evolving Management Landscape for Patients With Sickle Cell Disease: Opportunities, Challenges, and Emerging Agents for Therapy

Release Date: December 30, 2018
Expiration Date: December 30, 2019
Media: Internet - based

Activity Overview

This activity, Hematology Briefings™: The Evolving Management Landscape for Patients With Sickle Cell Disease: Opportunities, Challenges, and Emerging Agents for Therapy, developed in Physicians’ Education Resource®, LLC, established Hematology Briefings™ legacy format, is an online interactive monograph that provides treatment strategies for patients with sickle cell disease (SCD). This presentation features a national thought leader, Laura DeCastro, MD, who provides key insights.

Acknowledgement of Commercial Support

This activity is supported by an educational grant from Novartis Pharmaceuticals Corporation.

Instructions for This Activity and Receiving Credit

  • You will need to log in to participate in the activity.
  • Each presentation may contain an interactive question(s). You may move forward through the presentation; however, you may not go back to change answers or review audio files/content until you finish the presentation.
  • At the end of the activity, educational content/audio files will be available for your reference.
  • In order to receive a CME certificate, you must complete the activity.
  • Complete the Posttest and pass with a score of 70% or higher, complete the Evaluation, and then click on “Request for Credit.” You may immediately download a CME certificate upon completion of these steps.

Target Audience

This continuing medical education (CME) activity is intended for hematologists and physicians including pediatricians, who manage patients with sickle cell disease. Nurse practitioners, nurses, physician assistants, nurses, and other healthcare professionals involved in the treatment and management of patients with sickle cell disease will be invited to participate.

Learning Objectives

Upon successful completion of this activity, you should be better prepared to:

  • Identify patients with SCD and vaso-occlusive (VOC) symptoms earlier to initiate prompt intervention and preventive therapy
  • Recognize the acute and chronic complications associated with VOC phenomena in SCD
  • Distinguish current and emerging treatments for management of SCD and VOC crises and best practices for their use in patients’ managementv
  • Better utilize shared-decision making as a regular part of patients’ management of SCD, including discussion of therapy options and choices

Faculty, Staff, and Planners' Disclosures


Laura M. De Castro, MD, MHSc
Clinical Director benign Hematology
Associate Professor
Division of Hematology and Oncology
Department of Internal Medicine
Pittsburgh, Pennsylvania

Disclosures:Grant/Research Support: Bayer, Global Blood Therapeutics, Ironwood Pharmaceuticals, Pfizer; Consultant: Pfizer

The staff of PER® have no relevant financial relationships with commercial interests to disclose.

Disclosure Policy and Resolution of Conflicts of Interest (COI)

As a sponsor accredited by the ACCME, it is the policy of PER® to ensure fair balance, independence, objectivity, and scientific rigor in all of its CME activities. In compliance with ACCME guidelines, PER® requires everyone who is in a position to control the content of a CME activity to disclose all relevant financial relationships with commercial interests. The ACCME defines “relevant financial relationships” as financial relationships in any amount occurring within the past 12 months that creates a COI.

Additionally, PER® is required by ACCME to resolve all COI. PER® has identified and resolved all COI prior to the start of this activity by using a multistep process.

Off-Label Disclosure and Disclaimer

This CME activity may or may not discuss investigational, unapproved, or off-label use of drugs. Participants are advised to consult prescribing information for any products discussed. The information provided in this CME activity is for continuing medical and nursing education purposes only, and is not meant to substitute for the independent clinical judgment of a physician relative to diagnostic, treatment, or management options for a specific patient’s medical condition. The opinions expressed in the content are solely those of the individual faculty members and do not reflect those of PER®.

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