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Physicians' Education Resource®, LLC, is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

Physicians' Education Resource®, LLC, designates this enduring material for a maximum of 2.0 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Physicians' Education Resource®, LLC is approved by the California Board of Registered Nursing, Provider #16669 for 2.0 Contact Hours.

Acknowledgement of Commercial Support

This activity is supported by an educational grant/educational grant from AstraZeneca

Oncology Best Practice™: Choosing Therapies for Patients with EGFR-Mutant Lung Cancers: More Options... More Decisions... Better Outcomes

Release Date: February 28, 2017
Expiration Date: February 28, 2018
Media: Internet - based


Activity Overview

This activity features an expert presentation that illustrates approaches to choosing initial therapy for patients with advanced non–small cell lung cancers (NSCLCs) and mutations in the epidermal growth factor receptor (EGFR) gene, how to navigate the nuances regarding the evaluation of acquired resistance, newer approaches to molecular testing, choosing subsequent approaches to therapy, and managing patients with central nervous system metastases. The goal of this activity is to help physicians and nurses synthesize recent data sets on newly available and late-stage investigational strategies to manage their patients with EGFR-mutated, advanced NSCLCs and to place new evidence in its proper context for physicians and nurses engaged in the treatment/management of patients with these tumors.

Instructions for This Activity and Receiving Credit

  1. You will need to log in to participate in the activity.
  2. Each presentation may contain an interactive question(s). You may move forward through the presentation; however, you may not go back to change answers or review video files/content until you finish the presentation.
  3. At the end of the activity, educational content/video files will be available for your reference.
  4. In order to receive a CME certificate, participants must complete the activity.
  5. Complete the posttest and pass with a score of 70% or higher, complete the evaluation, and then click on request for credit. Participants may immediately download a CME certificate upon completion of these steps.

Target Audience

This educational activity is directed toward medical oncologists who treat patients with lung cancers. Nurse practitioners, nurses, physician assistants, pharmacists, researchers, and other healthcare professionals interested in the treatment of cancer are invited to participate.

Learning Objectives

At the conclusion of this activity, participants should be better prepared to:

  1. Detail evidence that underlies the application of optimized frontline strategies to manage EGFR-mutated, advanced non–small cell lung cancers (NSCLCs)
  2. Describe methods to optimize EGFR subtyping and emerging technologies that can practically facilitate tumor testing and overcome inherent challenges to optimized testing in community settings where advanced NSCLCs are managed
  3. Explain how to optimize the timing of clinical interventions in the relapsed, advanced NSCLC setting and the trial evidence that informs decision making to treat patients with EGFR-TKI resistance
  4. Address treatment-related toxicities and methods to optimize the management of central nervous system metastases in the care of patients with advanced NSCLCs.

Faculty, Staff, and Planners' Disclosures


Benjamin Levy, MD Associate Professor/Clinical Director, Medical Oncology
Johns Hopkins Medicine
Johns Hopkins Sidney Kimmel Cancer Center
Washington, DC

Disclosure: Consultant: AstraZeneca, Celgene, Merck, Pfizer, Bristol-Myers Squibb, Eli Lilly, Genentech; Speakers Bureau: Genentech 

Disclosure Policy and Resolution of Conflicts of Interest (COI)

It is the policy of PER® to ensure the fair balance, independence, objectivity, and scientific objectivity in all our CME activities. In accordance with ACCME guidelines, PER® requires everyone who is in a position to control the content of an educational activity, including spouses/partners, to disclose all relevant financial relationships with any commercial interest to participants as part of the activity planning process. PER® has implemented mechanisms to identify and resolve all conflicts of interest prior to release of this activity.

Staff and Planners’ Disclosures

The staff of Physicians' Education Resource®, LLC, have no relevant financial relationships with commercial interests to disclose.

Off-Label Disclosure and Disclaimer

This CME/CE activity may or may not discuss investigational, unapproved, or off-label uses of drugs. Participants are advised to consult prescribing information for any products discussed. The information provided in this CME/CE activity is for continuing medical and nursing education purposes only and is not meant to substitute for the independent clinical judgment of a physician or nurse relative to diagnostic, treatment, or management options for a specific patient’s medical condition.

The opinions expressed in the content are solely those of the individual faculty member and does not reflect those of PER® or any of the companies that provided commercial support for this activity.

CME Provider Contact Information

Physicians’ Education Resource®, LLC
2 Clarke Drive
Suite 100
Cranbury, NJ 08512

Hardware And Software Requirements 

Supported Browsers
Internet Explorer v.7 or greater (for Windows) | Mozilla Firefox v.2 or greater (for Windows, Mac, Linux)

Minimum System Requirements (Windows)

  • A Pentium-based PC or compatible computer
  • At least 64MB of RAM
  • Windows 95/98/NT/ME/2000/XP/Vista system software
  • Screen resolution of 1024 x 786 or larger recommended
  • PDF Reader: Adobe Reader 5.0 or higher, Foxit Reader 2.0 or likewise

Minimum System Requirements (Mac OS)

  • A PowerPC processor-based Macintosh computer
  • At least 64MB of RAM
  • Mac OS 7.5 or later
  • Screen resolution of 1024 x 786 or larger recommended
  • PDF Reader: Adobe Reader 5.0 or higher, Foxit Reader 2.0 or likewise

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