Accreditation/Credit Designation

Physicians' Education Resource®, LLC, is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

Physicians' Education Resource®, LLC, designates this enduring material for a maximum of 1.0 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Physicians’ Education Resource®, LLC is approved by the California Board of Registered Nursing, Provider #16669, for 1.0 Contact Hour.

Acknowledgment of Commercial Support

This activity is supported by an educational grant from Daiichi Sankyo, Inc.

Community Practice Connections™: Identifying and Treating Patients With TGCT: Best Practices for the Multidisciplinary Team

Release Date: June 30, 2019
Expiration Date: June 30, 2020
Media: Internet - based

Activity Overview

Tenosynovial giant cell tumors (TGCTs) come with particular challenges because the initial presentation of symptoms is nonspecific and slowly progressing, creating difficulties in distinguishing this disease from other causes of similar symptoms. This activity will review the pathophysiology and the current and emerging therapeutic options available to patients diagnosed with TGCT. Clinical expert William Tap, MD, will discuss the challenges regarding the identification and delayed diagnosis of this disease, and how to properly evaluate patients in order to improve recognition of this rare oncologic condition. Focus will be primarily on current treatment paradigms in the context of new developments, especially as relates to the colony-stimulating factor 1 receptor (CSF1R) inhibitors, which are currently in late-stage clinical development. In addition, this program will inform best practices in multidisciplinary management and care coordination to reduce diagnostic delays and optimize outcomes for patients with TGCT.

Benefits of Participating

  • Gain expert insights into current best practices for the recognition and diagnosis of TGCTs
  • Recognize current treatment options in the context of guidelines and expert-recommended best practices
  • Evaluate the latest safety and efficacy data from clinical trials in TGCT informing current options for clinical trial enrollment and therapies in late-stage development
  • Understand best practices for multidisciplinary care of patients with TCGT to optimize and expedite diagnosis

Acknowledgement of Commercial Support

This activity is supported by an educational grant from Daiichi Sankyo, Inc.

Instructions for This Activity and Receiving Credit

  • You will need to log in to participate in the activity.
  • Each presentation may contain an interactive question(s). You may move forward through the presentation; however, you may not go back to change answers or review video files/content until you finish the presentation.
  • At the end of the activity, educational content/video files will be available for your reference.
  • In order to receive a CME/CE certificate, you must complete the activity.
  • Complete the Posttest and pass with a score of 70% or higher, complete the Evaluation, and then click on “Request for Credit.” You may immediately download a CME/CE certificate upon completion of these steps.

Target Audience

This educational program is primarily directed toward orthopedic surgeons, sarcoma specialists, and oncologic surgeons who diagnose and/or treat patients with TGCT. Additionally, medical oncologists, fellows, nurses, nurse practitioners, physician assistants, and other healthcare professionals interested in the diagnosis, treatment, and management of TGCT are invited to participate.

Learning Objectives

Upon successful completion of this activity, you should be better prepared to:

  • Explain the challenges associated with differential diagnosis of TGCT and methods to facilitate its earlier diagnosis
  • Evaluate recent clinical trial efficacy and safety data of novel pharmacologic therapies for TGCT
  • Develop evidence-based treatment plans for the various forms of TGCT
  • Describe the role of multidisciplinary management as a best practice to optimize diagnosis and outcomes for patients with TGCT

Faculty, Staff, and Planners’ Disclosures


William D. Tap
William D. Tap, MD
Medical Oncologist
Chief, Sarcoma Medical Oncology Service
Memorial Sloan Kettering Cancer Center
New York, NY

Disclosures: Consultant: Eli Lilly, EMD Serono, Novartis, Eisai, Janssen, Immune Design, Adaptimmune, Daiichi Sanyko, Blueprint, Loxo, GlaxoSmithKline, Agios Pharmaceuticals, Nanocell.

The staff of Physicians' Education Resource®, LLC (PER®), have no relevant financial relationships with commercial interests to disclose.

Disclosure Policy and Resolution of Conflicts of Interest (COI)

As a sponsor accredited by the ACCME, it is the policy of PER® to ensure fair balance, independence, objectivity, and scientific rigor in all of its CME/CE activities. In compliance with ACCME guidelines, PER® requires everyone who is in a position to control the content of a CME/CE activity to disclose all relevant financial relationships with commercial interests. The ACCME defines “relevant financial relationships” as financial relationships in any amount occurring within the past 12 months that creates a COI.

Additionally, PER® is required by ACCME to resolve all COI. PER® has identified and resolved all COI prior to the start of this activity by using a multistep process.

Off-Label Disclosure and Disclaimer

This CME/CE activity may or may not discuss investigational, unapproved, or off-label use of drugs. Participants are advised to consult prescribing information for any products discussed. The information provided in this CME/CE activity is for continuing medical and nursing education purposes only and is not meant to substitute for the independent clinical judgment of a physician or nurse relative to diagnostic or treatment options for a specific patient’s medical condition.

The opinions expressed in the content are solely those of the individual faculty members, and do not reflect those of PER® or any of the companies that provided commercial support for this program.

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