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Accreditation/Credit Designation

Physicians' Education Resource®, LLC, is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

Physicians' Education Resource®, LLC, designates this enduring material for a maximum of 2.0 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Acknowledgment of Commercial Support

This activity is supported by educational grants from Eisai Inc. and Exelixis Inc.

Community Practice Connections™: Optimizing Care in the Era of an Expanding Armamentarium for Hepatocellular Carcinoma


Release Date: March 29, 2019
Expiration Date: March 29, 2020
Media: Internet - based

Activity Overview

Community Practice Connections™: Optimizing Care in the Era of an Expanding Armamentarium for Hepatocellular Carcinoma consists of short video interviews with leading experts in hepatocellular carcinoma (HCC) and brief summaries of clinical data related to the issues discussed. These issues include topics critical to the optimal management of patients with HCC, including first- and second-line treatment options, sequencing, and management of treatment-related toxicities.

Acknowledgement of Commercial Support

This activity is supported by educational grants from Eisai Inc. and Exelixis Inc.

Instructions for This Activity and Receiving Credit

  • You will need to log in to participate in the activity.
  • Each presentation may contain an interactive question(s). You may move forward through the presentation; however, you may not go back to change answers or review audio files/content until you finish the presentation.
  • At the end of the activity, educational content/audio files will be available for your reference.
  • In order to receive a CME/Ce certificate, you must complete the activity.
  • Complete the Posttest and pass with a score of 70% or higher, complete the Evaluation, and then click on “Request for Credit.” You may immediately download a CME/CE certificate upon completion of these steps.


Target Audience

This educational program is directed toward medical oncologists, surgical oncologists, radiation oncologists, hepatologists, and gastroenterologists interested in the treatment of HCC. Nurse practitioners, physician assistants, nurses, and other healthcare professionals involved in the treatment and management of patients with HCC are also invited to participate.

Learning Objectives

At the conclusion of this activity, you should be better prepared to:

  • Describe the mechanistic rationales underlying recent targeted drug development in HCC and how they relate to HCC biology
  • Summarize efficacy and safety outcomes from pivotal clinical trials of patients with advanced HCC
  • Evaluate recent clinical trial evidence and patient characteristics to inform optimized sequencing decisions in the management of patients with HCC
  • Outline strategies to mitigate the treatment-related toxicities of current and emerging therapies for the management of HCC

Faculty, Staff, and Planners’ Disclosures

R. Kate Kelley, MD, FACS
Associate Professor of Clinical Medicine
Department of Medicine, Division of Hematology/Oncology
Helen Diller Family Comprehensive Cancer Center
University of California, San Francisco
San Francisco, CA

Disclosures: Grant/Research Support: Agios, Bayer, BMS, AstraZeneca, Exelixis, Eli Lilly, GEO, Novartis, Taiho, Adaptimmune, Merck (all research support to institution); Other: IDMC Member (individual) − Genentech, Roche

Jennifer J. Knox, MD, MSc, FRCPC
Professor of Medicine, University of Toronto
Lead, Solid Tumor Medical Oncology
Princess Margaret Cancer Centre
Co-Director, McCain Centre for Pancreatic Cancer
Lewitt Chair in Pancreatic Cancer Research
Princess Margaret Cancer Centre at the OPG
Toronto, Ontario, Canada

Disclosures: Grant/Research Support: Merck, AstraZeneca; Consultant: Merck

Alan P. Venook, MD, FASCO
The Madden Family Distinguished Professor of Medical Oncology and Translational Research
Shorenstein Associate Director for Program Development
Helen Diller Family Comprehensive Cancer Center
University of California, San Francisco
San Francisco, CA

Disclosures: Grant/Research Support: Exelixis (to institution); Consultant: Eisai

Disclosure Policy and Resolution of Conflicts of Interest (COI)

As a sponsor accredited by the Accreditation Council for Continuing Medical Education (ACCME), it is the policy of PER® to ensure fair balance, independence, objectivity, and scientific rigor in all of its CME activities. In compliance with ACCME guidelines, PER® requires everyone who is in a position to control the content of a CME activity to disclose all relevant financial relationships with commercial interests. The ACCME defines “relevant financial relationships” as financial relationships in any amount occurring within the past 12 months that create a COI. Additionally, PER® is required by the ACCME to resolve all COI. We have identified and resolved all COI prior to the start of this activity by using a multistep process.

Off-Label Disclosure and Disclaimer

This CME/CE activity may or may not discuss investigational, unapproved, or off-label uses of drugs. Participants are advised to consult prescribing information for any products discussed. The information provided in this CME/CE activity is for continuing medical and nursing education purposes only and is not meant to substitute for the independent clinical judgment of a physician or nurse relative to diagnostic, treatment, and management options for a specific patient’s medical condition.

The opinions expressed in the content are solely those of the individual faculty members and do not reflect those of PER® or any of the companies that provided commercial support for this activity.


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