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Medical College of Wisconsin

The Medical College of Wisconsin is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

The Medical College of Wisconsin designates this live activity for a maximum of 1.0 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Acknowledgement of Commercial Support

This activity is supported by an educational grant from Omeros Corporation.

Evolving Strategies in the Management of HSCT Associated Thrombotic Microangiopathy

Evolving Strategies in the Management of HSCT Associated Thrombotic Microangiopathy


Saturday, February 22, 2020

Scientific Session: 7:00AM- 8:00AM Room: Cypress 3

Orlando World Center Marriott
8701 World Center Dr
Orlando, FL 32821

Overview

A very high rate of mortality and morbidity is associated with hematopoietic stem cell transplant (HSCT)-associated thrombotic microangiopathy (TA-TMA). The wide range of differing diagnostic criteria increases complexity in understanding clinically important syndromes such as TA-TMA, a complication that requires immediate clinical management following transplant. As such, transplant physicians need to be aware of all existing criteria and how they differ from each other. Conventional treatment strategies are highly inefficient; therefore, development of novel therapies that modify the activation of the complement cascade is in progress. This program will present case-based discussions that demonstrate the clinical significance of dysregulated complement activation in relation to TA-TMA, address diagnostic challenges, and incorporate new standards of patient care as new treatment options are developed and potentially introduced into the treatment paradigm.

This satellite symposium at the 2020 Transplantation and Cellular Therapy meeting will help clinicians recognize which patients will benefit from agents such as complement inhibitors, as well as navigate the changing treatment landscape of TA-TMA. An expert panel will present cases that incorporate the latest diagnostic criteria and clinical data for the treatment of TA-TMA.

Benefits of Attending

  • Increase knowledge and competence regarding diagnosis of TA-TMA
  • Heighten your ability to determine which patients will benefit from complement inhibition to manage TA-TMA
  • Learn about emerging standards of care for TA-TMA
  • Understand the pathophysiology and risk factors for TA-TMA, including genetic susceptibility
  • Utilize the proficiency of experts in TA-TMA to explore evolving concepts via a case-based symposium

Acknowledgement of Commercial Support

This activity is supported by an educational grant from Omeros Corporation.

Target Audience

This educational program is directed toward hematologists, medical oncologists, researchers, and investigators who treat or are interested in the treatment of hematologic malignancies. Other allied healthcare professionals, including nurse practitioners, physician assistants, and nurses involved in the treatment and management of patients with hematologic malignancies will also be invited to participate.

Learning Objectives

Upon completion of this activity, participants should be able to:

  • Review current diagnostic criteria for HSCT-associated TMA and ways to differentiate it from other stem cell transplant-associated complications with overlapping symptoms
  • Assess the role of dysregulated complement activation in the pathogenesis of HSCT-associated TMA
  • Discuss the rationale concerning the application of complement targeted therapies, including MASP-2 inhibitors, in the treatment of HSCT-associated TMA
  • Evaluate recent clinical trial data concerning the effectiveness of emerging therapies in the treatment of HSCT-associated TMA

Program Chair

Samer Khaled
Samer Khaled, MD
Associate Clinical Professor, Department of Hematology & Hematopoietic Cell Transplantation
City of Hope National Medical Center
Duarte, CA

Registration

This is a satellite symposium hosted by Physicians' Education Resource®, LLC, at the annual Transplantation and Cellular Therapy Meetings. Your registration to TCT is required to attend our meeting. For more info go to gotoper.com/go/TCT20HSCTper.




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