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Physicians' Education Resource®, LLC is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

Physicians' Education Resource®, LLC designates this live activity for a maximum of 1.0 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Physicians' Education Resource®, LLC is approved by the California Board of Registered Nursing, Provider #16669.

Acknowledgment of Commercial Support

This activity is supported by an educational grant from Jazz Pharmaceuticals.

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Oncology Best Practice™: Employing Effective Strategies to Address Posttransplant Obstacles in the Clinic: A Focus on GVHD and Hepatic VOD

Oncology Best Practice™: Employing Effective Strategies to Address Posttransplant Obstacles in the Clinic: A Focus on GVHD and Hepatic VOD


Oncology Best Practice™:
Employing Effective Strategies to Address Posttransplant Obstacles in the Clinic: A Focus on GVHD and Hepatic VOD

In order to request this CME/CE activity for your center, please contact Samantha Zelasko at SZelasko@gotoper.com or call (609) 325-4668

Overview

Recent Data for the Prevention and Treatment of Acute and Chronic Graft-vs-Host Disease and Hepatic VOD

Graft-vs-host disease (GVHD) and hepatic veno-occlusive disease (VOD) can occur after allogeneic hematopoietic stem cell transplantation (allo-HSCT) in patients with hematologic malignancies. The standard first-line treatment is systemic corticosteroids. However, the long-term use of corticosteroids is associated with severe adverse effects, and there are currently no FDA-approved therapies for steroid-refractory GVHD. Defibrotide sodium was recently approved for treatment of adults and children with hepatic VOD after allo-HSCT.

This activity will bring together renowned experts for an interactive symposium to discuss the impact of evolving evidence in the prevention and treatment of GvHD and hepatic VOD in patients with hematologic malignancies. The activity will focus on brief didactic presentations followed by real-world clinical case scenarios; challenging cases will be used in conjunction with an audience response system to assess knowledge gaps, practice patterns (“How would you treat this patient in light of the data?”), interpretation of clinical trial data, and changes in practice preferences (pre- vs posttest). Our expert panel discussion will also assess what the near future of the treatment of hematologic cancer may look like based on recent practice-changing evidence and data from ongoing clinical trials.

Acknowledgment of Commercial Support

This activity is supported by an educational grant from Jazz Pharmaceuticals.

Target Audience

This educational program is primarily directed toward community oncologists and hematologists who treat patients with hematologic malignancies. Additionally, fellows, nurses, nurse practitioners, physician assistants, and other healthcare professions (HCPs) involved in the treatment of hematologic malignancies will be invited to participate in the activity.

Educational Objectives

After completing this educational activity, participants should be better prepared to:

  • Summarize GVHD pathogenesis and diagnosis, as well as hepatic VOD diagnostic criteria to facilitate its identification and management
  • Review current prophylactic and treatment regimens for GVHD and hepatic VOD
  • Describe current evidence regarding emerging therapies in the treatment of GVHD and hepatic VOD
  • Identify and manage toxicities associated with GVHD and hepatic VOD treatment strategies

Chair

Corey Cutler, MD, MPH, FRCPC
Associate Professor of Medicine
Harvard Medical School
Dana-Farber Cancer Institute
Boston, MA






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