American Journal of Hematology / Oncology®
Breast Cancer
Current and Emerging Role of PARP Inhibitors in Breast Cancer

Angela DeMichele, MD, MSCE

Release Date: October 3, 2017
Expiration Date: October 3, 2018
Media: Print with online posttest, evaluation, and request for credit

Overview

This activity is designed to inform physicians about the current and developing strategies in treating patients who have breast cancer with PARP inhibitors.

Instructions for Participation/How to Receive Credit:

  1. Read the article in its entirety.
  2. Use the QR code or type education.gotoper.com/activity/ajho1706 into your Web browser to access the posttest.
  3. Complete and pass the posttest with a score of 70% or higher.
  4. Complete the evaluation and request for credit.

Target Audience

This activity is directed towards medical oncologists, primary care physicians, nurses, and nurse practitioners who treat and/or manage patients with breast cancer. Surgical oncologists, radiation oncologists, pathologists, internists, fellows, physician assistants, and other health care providers are also invited to participate.

Learning Objectives

After participating in this CME/CE activity, learners should be better prepared to:

  • Describe the biologic function of DNA repair, PARP inhibition, and the rationale behind targeted inhibition in breast cancer
  • Explain the development history of targeted PARP inhibitors in patients with breast cancer
  • Discuss emerging treatment options and ongoing trials of PARP inhibitors

The American Journal of Hematology/ Oncology® Editorial Board

Debu Tripathy, MD
Professor and Chairman
Department of Breast Medical Oncology
The University of Texas MD Anderson Cancer Center
Houston, TX
 

Disclosure: Grant/research support from Genentech/Roche, Pfizer, Puma Biotechnology Inc, and Novartis (clinical trial support contracted to the University of Southern California and MD Anderson Cancer Center); consultant for Eisai, OncoPlex Diagnostics, Merck, and Novartis.

Faculty

Angela DeMichele, MD, MSCE
Jill and Alan Miller Endowed Chair in Breast Cancer Excellence
Professor of Medicine (Hematology/Oncology) and Epidemiology
Co-Leader, Breast Cancer Program, Abramson Cancer Center
Senior Scholar, Center for Clinical Epidemiology, Biostatistics & Bioinformatics
University of Pennsylvania
Philadelphia, PA

Disclosure: Grant/Research Support: Calithera, Pfizer, Novartis, Janssen, Genentech; Consultant: Pfizer, Calithera, Novartis

Staff/Planner Disclosures and Conflict of Interest Resolution

The staff of Physicians’ Education Resource®, LLC (PER®), and the editorial staff of The American Journal of Hematology/Oncology® have no relevant financial relationships with commercial interests to disclose.

It is the policy of PER® to ensure fair balance, independence, objectivity, and scientific objectivity in all of our CME/CE activities. In accordance with ACCME guidelines, PER® requires everyone who is in a position to control the content of an educational activity, including spouses/partners, to disclose all relevant financial relationships with any commercial interest to participants as part of the activity planning process. PER® has implemented mechanisms to identify and resolve all conflicts of interest prior to release of this activity.

Accreditation/Credit Designation

Physicians’ Education Resource®, LLC, is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

Physicians’ Education Resource®, LLC, designates this enduring material for a maximum of 1.0 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Physicians' Education Resource®, LLC, is approved by the California Board of Registered Nursing, Provider #16669 for 1.0 Contact Hour.

This activity is funded by PER®

Off-Label Disclosure and Disclaimer

This continuing medical and nursing education activity may or may not discuss investigational, unapproved, or off-label uses of drugs. Participants are advised to consult prescribing information for any products discussed. The information provided in this CME/CE activity is for continuing medical and nursing education purposes only and is not meant to substitute for the independent medical judgment of a physician or nurse relative to diagnostic, treatment, and management options for a specific patient’s medical condition.

Disclaimer

The opinions expressed in the content are solely those of the individual faculty members and do not reflect those of Physicians’ Education Resource®, LLC.

Contact information for questions about the activity:
Physicians’ Education Resource®, LLC
2 Clarke Drive
Suite 110
Cranbury, NJ 08512
Phone: (888) 949-0045
E-mail: info@gotoper.com



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