Release Date: September 28, 2015
Expiration Date: September 28, 2016
Media: Internet - based
This activity is structured using the Oncology Consultation® platform which features audio clips of two breast cancer experts engaging in case-based discussions of patient management and treatment issues. This educational program features two clinical scenarios that touch upon issues of HER2 equivocal status, molecular profiling for adjuvant decision making, emerging molecular assays for assessment of clinical trial eligibility in the metastatic setting, and germline testing in triple-negative breast cancer. Interactive questions are integrated throughout the cases to reinforce learning.
CME Activity Table of Content
- Case of ER+, HER2-Equivocal Breast Cancer
- Case of TNBC in a Woman With a Family History
- Key Take-Aways
Instructions For This Activity & Receiving Credit
This activity is directed toward medical and surgical oncologists who treat patients with breast cancer. Pathologists, fellows, nurses, nurse practitioners, physician assistants, and other healthcare professionals (HCPs) involved in the management of patients with breast cancer will also be invited to participate.
At the conclusion of this activity, you should be better prepared to:
- Integrate biomarkers, molecular assays, and other risk assessment tools in treatment decision making for breast cancer, when appropriate.
- Evaluate emerging clinical data regarding biomarkers and prognostic and predictive molecular assays along with evolving strategies for the treatment of breast cancer, and apply clinical trial data appropriately in order to optimize the outcome of individual patients.
Faculty, Staff, and Planners' Disclosures
Debu Tripathy, MD
Professor of Medicine and Chair
Department of Breast Medical Oncology
The University of Texas MD Anderson Cancer Center
Disclosure: Grant/Research Support: Genentech/Roche, Pfizer, Puma Inc, Novartis (clinical trial support contracted to the University of Southern California and MD Anderson Cancer Center); Consultant: Eisai, Onco-Plex Diagnostics, Merck, Novartis.
Joyce O'Shaughnessy, MD
Co-Director, Breast Cancer Research
Baylor Charles A. Sammons Cancer Center
The US Oncology Network
Disclosure: Consultant: Arno Therapeutics, AstraZeneca, Celgene, Corcept Therapeutics, Eisai, Genentech, GlaxoSmithKline, Lilly, J&J, Merrimack, Novartis, Pfizer, Roche, Sanofi, Takeda Pharmaceutical, MedFusion
The following individuals have no relevant financial relationships with commercial interests:
The staff of PER®, LLC (Tiffany Fattizzi and Ann C. Lichti, CHCP), Kim Farina, PhD (medical writer), and Margie Schulz (medical reviewer).
Accreditation/Designation of Credit Statement
Physicians' Education Resource®, LLC, is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.
Physicians' Education Resource®, LLC, designates this enduring material for a maximum of 2.0 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Acknowledgment of Commercial Support
This activity is supported by educational grants from Genomic Health and Foundation Medicine.
Disclosure Policy and Resolution of Conflicts of Interest (COI)
It is the policy of PER® to ensure the fair balance, independence, objectivity, and scientific objectivity in all of our CME activities. In accordance with ACCME guidelines, PER® requires everyone who is in a position to control the content of an educational activity, including spouses/partners, to disclose all relevant financial relationships with any commercial interest to participants as part of the activity planning process. PER® has implemented mechanisms to identify and resolve all conflicts of interest prior to release of this activity.
Off-Label Disclosure and Disclaimer
This CME activity may or may not discuss investigational, unapproved, or off-label use of drugs. Participants are advised to consult prescribing information for any products discussed. The information provided in this CME activity is for continuing medical education purposes only and is not meant to substitute for the independent medical judgment of a physician relative to diagnostic and treatment options for a specific patient's medical condition.
The opinions expressed in the content are solely those of the individual faculty members and do not reflect those of Physicians' Education Resource®, LLC, or any of the companies that provided commercial support for this activity.
Hardware And Software Requirements
Internet Explorer v.7 or greater (for Windows) | Mozilla Firefox v.2 or greater (for Windows, Mac, Linux)
Minimum System Requirements (Windows)
- A Pentium-based PC or compatible computer
- At least 64MB of RAM
- Windows 95/98/NT/ME/2000/XP/Vista system software
- Screen resolution of 1024 x 786 or larger recommended
- PDF Reader: Adobe Reader 5.0 or higher, Foxit Reader 2.0 or likewise