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Physicians' Education Resource®, LLC, is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

Physicians' Education Resource®, LLC, designates this enduring material for a maximum of 1.5 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Resources

PER Pulse™ Recaps highlight key elements of the Community Practice Connections™: The Emergence of CAR-T Cell Therapy for Hematologic Malignancies: Moving From Bench to Bedside online CME activity.

Acknowledgment of Commercial Support

This activity is supported by an educational grant from Juno Therapeutics.

Community Practice Connections™: The Emergence of CAR-T Cell Therapy for Hematologic Malignancies: Moving From Bench to Bedside

Release Date: December 29, 2016
Expiration Date: December 29, 2017
Media: Internet - based

Activity Overview

The Community Practice Connections™: The Emergence of CAR-T Cell Therapy for Hematologic Malignancies: Moving From Bench to Bedside is a series of short video interviews from leading oncology experts who address a variety of questions concerning the use of chimeric antigen receptor (CAR)-modified T-cell therapies in a number of hematologic malignancies, including acute lymphoblastic leukemia (ALL) and non-Hodgkin lymphoma. This activity is intended to meet the educational needs of the busy clinician who manages some of the most difficult-to-treat hematologic malignancies.

Acknowledgment of Commercial Support

This activity is supported by an educational grant from Juno Therapeutics.

CME/CE Activity Table of Contents

  • Module I: CAR-T Cell Technology
  • Module II: Clinical Experience in Acute Lymphoblastic Leukemia
  • Module III: Clinical Experience in Other Hematologic Malignancies
  • Module IV: Managing Adverse Events Related to CAR-T Cell Therapy

Instructions For This Activity & Receiving Credit

  • You will need to login to participate in the activity.
  • Each presentation may contain an interactive question(s). You may move forward through the presentation; however, you may not go back to change answers or review videos/content until you finish the presentation.
  • At the end of the activity, "educational content/video" will be available for your reference.
  • In order to receive a CME certificate, participants must complete the activity.
  • Complete the posttest and pass with a score of 70% or higher, complete the evaluation and then click on request for credit. Participants may immediately download a CME certificate upon completion of these steps.


Target Audience

This activity is intended for medical oncologists, hematologists, and other oncology healthcare professionals interested in the latest advances in the use of CAR-T cell therapy for patients with hematologic malignancies. Fellows, researchers, nurses, nurse practitioners, physician assistants, and other healthcare professionals interested in the treatment of patients with hematologic malignancies may also participate.

Learning Objectives

At the conclusion of this activity, you should be better prepared to:

  1. Describe the structure and function of the CAR and the mechanism of action of CAR-T cells in lymphoma
  2. Review clinical trial evidence in ALL and describe where CAR-T cell therapies might fit in the treatment landscape
  3. Review clinical trial evidence in other lymphoid malignancies and describe where CAR-T cell therapy might fit in the treatment landscape of those malignancies
  4. Identify and discuss the management of toxicities of CAR-T cell therapies

Disclosure Policy and Resolution of Conflicts of Interest (COI)

As a sponsor accredited by the ACCME, it is the policy of PER® to ensure fair balance, independence, objectivity, and scientific rigor in all of its CME activities. In compliance with ACCME guidelines, PER® requires everyone who is in a position to control the content of a CME activity to disclose all relevant financial relationships with commercial interests. The ACCME defines “relevant financial relationships” as financial relationships in any amount occurring within the past 12 months that create a COI.

Additionally, PER® is required by ACCME to resolve all COI. PER® has identified and resolved all COI prior to the start of this activity by using a multistep process.

Faculty, Staff, and Planners' Disclosures

Stephen J. Forman, MD
Chair and Professor
Department of Hematology and Hematopoietic Cell Transplantation
Director, Hematologic Malignancies and Stem Cell Transplantation Institute
Director, T Cell Therapeutics Research Laboratory
Professor, Department of Medical Oncology
City of Hope
Duarte, CA
Disclosure: Grant/Research Support: Mustang 
Therapeutics.
Rebecca A. Gardner, MD
Assistant Professor, Center for Clinical and Translational Research
Seattle Children’s Hospital
Seattle, WA
Disclosure: No financial relationships to disclose.
Jae Park, MD
Assistant Attending Physician
Department of Medicine
Leukemia Service
Memorial Sloan Kettering Cancer Center
New York, NY
Disclosure: Grant/Research Support: Juno Therapeutics.
Cameron Turtle, MBBS, PhD, FRCPA
Associate Member, Clinical Research
Division
Assistant Professor
University of Washington School of Medicine
Fred Hutchinson Cancer Research Center
Seattle, WA
Disclosure:Grant/Research Support: Juno Therapeutics; Consultant: Juno Therapeutics, Seattle Genetics.

The staff of Physicians’ Education Resource®, LLC have no relevant financial relationships with commercial interests to disclose.

Off-Label Disclosure and Disclaimer

This CME activity may or may not discuss investigational, unapproved, or off-label uses of drugs. Participants are advised to consult prescribing information for any products discussed. The information provided in this CME activity is for continuing medical and nursing education purposes only and is not meant to substitute for the independent clinical judgment of a physician relative to diagnostic or treatment options for a specific patient’s medical condition. The opinions expressed in the content are solely those of the individual faculty members and do not reflect those of PER®.

The opinions expressed in the content are solely those of the individual faculty members and do not reflect those of PER®, or any of the companies that provided commercial support for this activity.

CME Provider Contact Information

Physicians’ Education Resource®, LLC
666 Plainsboro Road, Suite 356
Plainsboro, NJ 08536
Toll Free: 888-949-0045
Local: 609-378-3701
Fax: 609-257-0705
info@gotoper.com








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