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Accreditation/ Credit Designation

Physicians' Education Resource®, LLC, is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

Physicians' Education Resource®, LLC, designates this enduring material for a maximum of 1.5 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.


PER Pulse™ Recaps highlight key elements of the Advances in™ Immunotherapy: The Expanding Potential of CAR T-Cell Therapy for Hematologic Malignancies online CME activity.

Acknowledgment of Commercial Support

This activity is supported by an educational grant from Novartis Pharmaceuticals Corporation.

Advances in™ Immunotherapy: The Expanding Potential of CAR T-Cell Therapy for Hematologic Malignancies

Release Date: December 30, 2016
Expiration Date: December 30, 2017
Media: Internet - based


Activity Overview

This activity will focus on the evolution of immuno-oncology treatments and the evolving potential in treating hematologic malignancies and will include 2 expert video interviews. The expert faculty will discuss new data, provide perspective on how the evolving concepts may impact the future, and guide participants on potential application to clinical practice.

CME Activity Table of Contents

  • CAR-T Cell Technology: Design and Rationale
  • The Potential for CAR-T Cells in Clinical Practice for Hematologic Malignancies
  • Safety and Toxicity Management of CAR-T Cell Technology: Pediatric and Adult Patients
  • Coordinating Care Between Academic Centers and Community Practices
  • Future of CAR-T Cell Technology

Instructions For This Activity & Receiving

  • You will need to login to participate in the activity.
  • Each presentation may contain an interactive question(s). You may move forward through the presentation; however, you may not go back to change answers or review videos/content until you finish the presentation.
  • At the end of the activity, "educational content/video" will be available for your reference.
  • In order to receive a CME certificate, participants must complete the activity.
  • Complete the posttest and pass with a score of 70% or higher, complete the evaluation and then click on request for credit. Participants may immediately download a CME certificate upon completion of these steps.

Target Audience

This educational activity is directed toward medical oncologists who treat patients with hematologic malignancies. Fellows, nurses, nurse practitioners, physician assistants and other healthcare professions (HCPs) involved in the treatment of hematologic malignancies are also invited to participate.

Educational Objectives

At the conclusion of this activity, participants should be better prepared to:

  • Describe the structure and function of the CAR and the mechanism of action of CAR T cells in lymphoma
  • Review clinical trial evidence in acute lymphoblastic leukemia (ALL) and describe where CAR-T cell therapies might fit in the treatment landscape
  • Review clinical trial evidence in other lymphoid malignancies and describe where CAR-T cell therapy might fit in the treatment landscape
  • Identify and discuss the management of toxicities of CAR-T cell therapies

Faculty, Staff, and Planners' Disclosures


Jae H. Park, MD
Assistant Attending Physician
Department of Medicine, Leukemia Service
Memorial Sloan Kettering Cancer Center
New York, NY
Disclosure: Grant/Research Support: Juno Therapeutics, Genentech; Consultant: Amgen, Novartis.


Daniel J. DeAngelo, MD, PhD
Director of Clinical and Translational Research, Adult Leukemia
Institute Physician
Associate Professor of Medicine, Harvard Medical School
Disclosure: No relevant financial relationships with commercial interests


The staff of PER®, LLC have no relevant financial relationships with commercial interests.

Disclosure Policy and Resolution of Conflicts of Interest (COI)

It is the policy of PER® to ensure the fair balance, independence, objectivity, and scientific objectivity in all of our CME activities. In accordance with ACCME guidelines, PER® requires everyone who is in a position to control the content of an educational activity, including spouses/partners, to disclose all relevant financial relationships with any commercial interest to participants as part of the activity planning process. PER® has implemented mechanisms to identify and resolve all conflicts of interest prior to release of this activity.

Off-Label Disclosure and Disclaimer

This CME/CE activity may or may not discuss investigational, unapproved, or off-label uses of drugs. Participants are advised to consult prescribing information for any products discussed. The information provided in this CME/CE activity is for continuing medical education purposes only, and is not meant to substitute for the independent medical judgment of a physician or nurse relative to diagnostic, treatment, or management options for a specific patient's medical condition.

The opinions expressed in the content are solely those of the individual faculty members, and do not reflect those of Physicians’ Education Resource®, LLC, or any of the companies that provided commercial support for this activity.

CME Provider Contact Information

Physicians’ Education Resource®, LLC
666 Plainsboro Road, Suite 356
Plainsboro, NJ 08536
Toll Free: 888-949-0045
Local: 609-378-3701
Fax: 609-257-0705

Hardware And Software Requirements 

Supported Browsers
Internet Explorer v.7 or greater (for Windows) | Mozilla Firefox v.2 or greater (for Windows, Mac, Linux)

Minimum System Requirements (Windows)

  • A Pentium-based PC or compatible computer
  • At least 64MB of RAM
  • Windows 95/98/NT/ME/2000/XP/Vista system software
  • Screen resolution of 1024 x 786 or larger recommended
  • PDF Reader: Adobe Reader 5.0 or higher, Foxit Reader 2.0 or likewise

Minimum System Requirements (Mac OS)

  • A PowerPC processor-based Macintosh computer
  • At least 64MB of RAM
  • Mac OS 7.5 or later
  • Screen resolution of 1024 x 786 or larger recommended
  • PDF Reader: Adobe Reader 5.0 or higher, Foxit Reader 2.0 or likewise

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