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Concluded -- 17th International Congress on Hematologic Malignancies®: Focus on Leukemias, Lymphomas and Myeloma (2013)


Overview

The 17th Annual International Congress on Hematologic Malignancies®: Focus on Leukemias, Lymphomas, and Myeloma will provide a unique opportunity for medical oncologists, hematologists, and other health care professionals to learn from and to interact with international leaders in the field of hematologic malignancies in order to increase knowledge, apply new data to practice, and improve patient outcomes.

Target Audience

This CME activity is directed toward medical oncologists and hematologists interested in the treatment of patients with hematologic malignancies. Fellows, nurse practitioners, nurses, physician assistants, pharmacists, researchers, and other health care professionals interested in the treatment of hematologic malignancies are also invited to participate.

Learning Objectives

At the conclusion of this activity, you should be better prepared to:
  • Evaluate emerging clinical data regarding new agents and evolving strategies for the treatment of hematologic malignancies, and apply clinical trial data appropriately in order to optimize the outcome of individual patients
  • Integrate genomic and molecular biomarkers when appropriate into risk assessment and treatment selection for patients with hematologic malignancies
  • Compare efficacy and safety data supporting treatment options for lymphoma (including indolent and aggressive B cell lymphomas, Hodgkin lymphoma, and T cell lymphomas) in order to optimize outcomes for individual patients
  • Individualize therapy for patient with newly diagnosed and relapsed/refractory multiple myeloma based on assessment of transplant eligibility, patient and tumor characteristics, and risk/benefit profiles of available regimens
  • Discuss strategies for the first-line treatment of chronic-phase chronic myeloid leukemia, as well as monitoring guidelines and options for patients in accelerated- or blast-phase
  • Evaluate the efficacy and safety of standard and emerging treatment approaches for patients with acute leukemias, myelodysplastic syndrome, and myeloproliferative disorders in order to personalize therapy for individual patients.
  • Review recent advances in treatment options for chronic lymphocytic leukemia, including the use of prognostic factors, to optimize outcomes.

Disclosure Policy and Resolution of Conflicts of Interest (COI)

As a sponsor accredited by the Accreditation Council for Continuing Medical Education (ACCME), it is the policy of PER to ensure fair balance, independence, objectivity, and scientific rigor in all of its CME activities. PER additionally requires everyone who is in a position to control the content of a CME activity to disclose all relevant financial relationships with commercial interests. The ACCME defines “relevant financial relationships” as financial relationships in any amount occurring within the past 12 months that create a COI. All relevant financial relationships with any commercial interests are disclosed to participants prior to the beginning of PER’s CME activities. PER has identified and resolved all COI prior to the start of this activity using a multi-step process.

Off-Label Disclosure and Disclaimer

This CME activity will contain discussions about off-label/unapproved uses of drugs including but not limited to brentuximab vedotin, carfilzomib, pomalidomide, doxorubicin, dexamethasone, bortezomib, bendamustine, melphalan, lenalidomide, delanzomib, ibrutinib, idelalisib, rituximab for ITP, romiplostim and eltrombopag for pediatric ITP, E5501 (avatrombopag maleate) for ITP, ABT‑199, IPI-145, SCDT 2980s, ofatumumab, aurora kinase inhibitors, GS-1101, PCYC-32765, IP2101, ibritumomab tiuxetan, interferon in MPNs, rigosertib, clofarabine for MDS, ponatinib, blinatumomab, azacitidine, decitabine and clofarbine.
 
For additional information about approved uses, including approved indications, contraindications, and warnings, participants are advised to consult prescribing information for all products discussed or consult the Physicians’ Desk Reference. The information provided in this CME activity is for continuing medical education purposes only and is not meant to substitute for the independent medical judgment of a physician relative to diagnostic and treatment options for a specific patient’s medical condition.
 
Disclaimer
The opinions expressed in the content are solely those of the individual faculty members and do not reflect those of Physicians’ Education Resource®, LLC, or any of the companies that provided commercial support for this CME activity.

Chair

Andrew D. Zelenetz, MD, PhD
Memorial Sloan-Kettering Cancer Center
New York, NY

Program Committee

Sundar Jagannath, MD
The Tisch Cancer Institute
Mount Sinai School of Medicine
The Mount Sinai Medical Center
New York, NY
  Charles Schiffer, MD
Karmanos Cancer Institute
Wayne State University School of Medicine
Detroit, MI
  William G. Weirda, MD, PhD
The University of Texas
MD Anderson Cancer Center
Houston, TX

Faculty

Ranjana Advani, MD
Stanford Cancer Institute
Stanford School of Medicine
Stanford, CA

Nancy Bartlett, MD
Washington University School of Medicine
St. Louis, MO
 
James Berenson, MD
Institute for Myeloma and Bone Cancer Research
West Hollywood, CA
 
Donald Berry, PhD
University of Texas MD Anderson Cancer Center
Houston, TX
 
Jennifer Brown, MD, PhD

Dana Farber Cancer Institute
Harvard Medical School
Boston, MA
 
Patrick Brown, MD

Sidney Kimmel Comprehensive Cancer Center
Johns Hopkins University School of Medicine
Baltimore, MD

James Bussel, MD
Weill Cornell Medical College
New York, NY
 
Bruce Cheson, MD

Georgetown Lombardi Comprehensive Cancer Center
Washington, DC

Nicholas Chiorazzi, MD
Weill Cornell Medical College
New York, NY
 
Daniel DeAngelo, MD, PhD

Dana Farber Cancer Institute
Boston, MA
 
Harry Erba, MD

University of Alabama Birmingham School of Medicine
Birmingham, AL

Eric Feldman, MD
Weill Cornell Medical College
New York, NY
 
Alessandra Ferrajoli, MD

University of Texas MD Anderson Cancer Center
Houston, TX
 
Jonathan Friedberg, MD, MMsc

James P. Wilmont Cancer Center
University of Rochester Medical Center
Rochester, NY

Randy Gascoyne, MD
BC Cancer Agency
Vancouver, BC, Canada
 
Andre Goy, MD

John Theurer Cancer Center at Hackensack University Medical Center
Hackensack, NJ
 
Paul Hamlin, MD

Memorial Sloan Kettering Cancer Center
New York, NY

Steven Horwitz, MD
Memorial Sloan Kettering Cancer Center
New York, NY
  Virginia Klemik, MD
Memorial Sloan Kettering Cancer Center
New York, NY
 
Thomas Kipps, MD, PhD

UCSD Moores Cancer Center
La Jolla, CA

Ola Landgren, MD
National Cancer Institute
Bethesda, MD

Ross Levine, MD
Memorial Sloan Kettering Cancer Center
New York, NY

Michael Mauro, MD
Oregon Health and Science University
Portland, OR

Ari Melnick, MD
Weill Cornell Medical College
New York, NY

Ruben Mesa, MD, FACP
Mayo Clinic Cancer Center
Scottsdale, AZ
 
Craig Moskowitz, MD

Memorial Sloan Kettering Cancer Center
New York, NY
 
Nikhil Munshi, MD

Dana Farber Cancer Institute
Harvard Medical School
Boston, MA

Daniel O. Persky, MD
Yale Cancer Center
New Haven, CT

Lauren Pinter-Brown, MD, FACP
Geffen School of Medicine at UCLA
Los Angeles, CA
 
Pierluigi Porcu, MD

The Ohio State University Comprehensive Cancer Center
Arthur G. James Cancer Hospital
Richard Solove Research Institute
Columbus, OH
 
Richard Silver, MD

Weill Cornell Medical College
New York, NY
 
David Steensma, MD

Dana Farber Cancer Center
Harvard Medical School
Boston, MA

Richard Stone, MD
Harvard Medical School
Boston, MA
 
Moshe Talpaz, MD

University of Michigan Comprehensive Cancer Center
Ann Arbor, MI

Joachim Yahalom, MD
Memorial Sloan Kettering Cancer Center
New York, NY
 
Anas Younes, MD
The University of Texas MD Anderson Cancer Center
Houston, TX

Faculty and Staff Disclosures

The following individuals have relevant financial relationships with commercial interests to disclose:

Ranjana Advani, MD – Grant/Research Support – Allos Therapeutics, Seattle Genetics; Nancy Bartlett, MD – Paid Travel Expenses (ASCO Poster Presentation) – Seattle Genetics; James Berenson, MD – Grant/Research Support – Amgen, Novartis, Medtronic, Onyx, Millennium; Consultant: Onyx, Millennium, Amgen, Medtronic; Speaker’s Bureau – Onyx, Millenium, Amgen, Medtronic; Donald Berry PhD – Consultant – Berry Consultants, LLC; Stock/Shareholder – Co-owner of Berry Consultants, LLC; Jennifer Brown, MD, PhD – Grant/Research Support – Genzyme (now sanofi-aventis); Consultant – Genentech, Emergent, sanofi-aventis, Celgene, Onyx; James Bussel, MD – Grant/Research Support – Amgen, Cangene, GlaxoSmithKline, Genzyme, IgG of America, Immunomedics, Ligand, Eisai Inc, Shionogi, Sysmex; Consultant/Ad Board – Amgen, GlaxoSmithKline, Ligand, Shionogi, Symphogen, Eisai, Inc; Stock/Shareholder – Amgen, GlaxoSmithKline;  Bruce Cheson, MD – Consultant – Genentech, Celgene; Nicholas Chiorazzi, MD – Grant/Research Support: Pharmacyclics; Stock/Shareholder – Kinemed, Inc.; Daniel DeAngelo, MD, PhD – Consultant – Amgen; Harry Erba, MD – Grant/Research Support – Novartis, , Celator, GenzymeMillennium; Speaker’s Bureau – Celgene, Novartis, Incyte; Alessandra Ferrajoli, MD – Grant/Research Support – Celgene, GlaxoSmithKline; Other Support (Advisory Board) – Celgene, Pharmacyclics; Jonathan Friedberg, MD – Consultant – Genentech, Bayer, Seattle Genetics; Other Support (Data and Safety Monitoring): Lilly; Randy Gascoyne, MD, FRCPC – Grant/Research Support – Seattle Genetics, Roche Canada; Consultant – Seattle Genetics, Celgene, Janssen, Genentech, Roche; Speaker’s Bureau – Seattle Genetics; Andre Goy, MD – Clinical Trial Support Through Institutions; Speaker’s Bureau – Millennium; Advisory Board – Millennium, Celgene, Pharmacyclics, Johnson & Johnson, Seattle Genetics, Pfizer; Paul Hamlin, MD – Grant/Research Support – Spectrum, GlaxoSmithKline, Pfizer, Seattle Genetics; Consultant – Genentech, Gilead, Spectrum; Steven Horwitz, MD – Grant/Research Support – Celgene, Allos, Seattle Genetics, Infinity, Kyowa, Millennium; Consultant – Celgene, Allos, Seattle Genetics, Bristol Myers Squibb, Genzyme, Kyowa, Johnson & Johnson, Janssen, Millennium; Sundar Jagannath, MD – Consultant – Merck, Celgene, Millennium; Thomas Kipps, MD, PhD – Grant/Research Support – Abbott, Celgene, Genentech, Pharmacyclics, AstraZeneca, Amgen, Medimmude, Gilead; Consultant – Onyx; Stock/Shareholder – Eclipse Tx, Ingenica; Michael Mauro, MD – Grant/Research Support – Novartis, Bristol Myers Squibb, Ariad; Consultant – Novartis, Bristol Myers Squibb, Ariad, Pfizer; Ruben Mesa, MD, FACP – Research Support – Inyte, Celgene, Gilead, Infinity, Lilly, NS Pharma; Ari Melnick, MD – Grant/Research Support – NCI, Leukemia and Lymphoma Society; Consultant – Celgene; Speaker’s Bureau – Genentech; Craig Moskowitz, MD – Grant/Research Support – Seattle Genetics, Roche, GlaxoSmithKline, Plexxikon, Cephalon; Consultant – Seattle Genetics, Roche, GlaxoSmithKline; Nikhil Munshi, MD – Consultant – Celgene, Merck, Millenium, Onyx; Daniel Persky, MD – Grant/Research Support – Merck; Lauren Pinter-Brown, MD, FACP – Consultant – Spectrum; Pierluigi Porcu, MD – Grant/Research Support – Millennium; Consultant – Hospira, Elorac; Charles Schiffer, MD – Grant/Research Support – Ariad, Celgene, Ambit, Bristol Myers Squibb; Consultant – Eisai, Teva, Celgene, Novartis, Bristol Myers Squibb; Richard Silver, MD – Grant/Research Support – Merck; Clinical Trial Investigator – Interferon in treatment in early phase myleofibrosis; David Steensma, MD – Consultant – Amgen, Array, Biopharma, Boehringer Ingelheim, Celgene; Richard Stone, MD – Grant/Research Support – Novartis; Consultant – Teva, Seattle Genetics, Amgen; Other Support – Sunesis (OSMB), Amgen (Steering Committee); Moshe Talpaz, MD – Grant/Research Support – Novartis, Ariad, Bristol Myers Squibb, sanofi-aventis, Incyte; Consultant – Novartis, Ariad, Bristol Myers Squibb, Teva; Speaker’s Bureau – Novartis, Ariad; William Wierda, MD, PhD – Grant/Research Support – Abbott, GlaxoSmithKline, Genentech/Roche; Consultant – Celgene, Genentech/Roche, Merck, sanofi-aventis; Speaker’s Bureau – Celgene, GlaxoSmithKline, Genentech/Roche; Anas Younes, MD – Grant/Research Support – Seattle Genetics, Millennium, Johnson & Johnson, Gilead, Novartis; Consultant – Seattle Genetics, Millennium, ISIS, Novartis; Andrew Zelenetz, MD – Research – Roche, GlaxoSmithKline, Genentech; Consulting – Seattle Genetics, sanofi-aventis USA, GlaxoSmithKline, Gilead, Cephalon, Celgene; Other – Scientific Advisor – Cancer Genetics
 
The following individuals have no relevant financial relationships with commercial interests to disclose: Patrick Brown, MD; Eric Feldman, MD; Virginia Klimek, MD, Ola Landgren, MD, PhD; Ross Levine, MD; Joachim Yahalom, MD
 
Physicians’ Education Resource®, LLC Planning Staff – Ann C. Lichti, CCMEP, Tristan Nelsen, MNM, CMP and Susan Peck, PhD.

Off-Label Disclosure and Disclaimer
This CME activity will contain discussions about off-label/unapproved uses of drugs including but not limited to brentuximab vedotin, carfilzomib, pomalidomide, doxorubicin, dexamethasone, bortezomib, bendamustine, melphalan, lenalidomide, delanzomib, ibrutinib, idelalisib, rituximab for ITP, romiplostim and eltrombopag for pediatric ITP, E5501 (avatrombopag maleate) for ITP, ABT‑199, IPI-145, SCDT 2980s, ofatumumab, aurora kinase inhibitors, GS-1101, PCYC-32765, IP2101, ibritumomab tiuxetan, interferon in MPNs, rigosertib, clofarabine for MDS, ponatinib, blinatumomab, azacitidine, decitabine and clofarbine.
 
For additional information about approved uses, including approved indications, contraindications, and warnings, participants are advised to consult prescribing information for all products discussed or consult the Physicians’ Desk Reference. The information provided in this CME activity is for continuing medical education purposes only and is not meant to substitute for the independent medical judgment of a physician relative to diagnostic and treatment options for a specific patient’s medical condition.
 
Disclaimer
The opinions expressed in the content are solely those of the individual faculty members and do not reflect those of Physicians’ Education Resource®, LLC, or any of the companies that provided commercial support for this CME activity.

    Agenda


    Friday, February 15, 2013  
    7:00 am Registration and Breakfast  
    8:00 am Welcome Andrew Zelenetz, MD, PhD
    T-Cell Lymphoma Moderator: Steven Horwitz, MD
    8:05 am Introductions & Pre-session Outcomes Survey Steven Horwitz, MD
    8:15 am Lymphoma Classification and the Impact of Genomics Randy Gascoyne, MD
    8:35 am Initial Management of Peripheral T Cell Lymphoma: If CHOP is no good, what is? Steven Horwitz, MD
    8:50 am Comment Ranjana Advani, MD
      Debate: Role of HDT/ASCR in initial management of PTCL Moderator: Steven Horwitz, MD
    8:55 am Pro Lauren Pinter Brown, MD, FACP
    9:10 am Con Pier Luigi Porcu, MD
    9:25 am Management of CD30+ Lymphoma Ranjana Advani, MD
    9:40 am Comment Steven Horwitz, MD
    9:45 am Break  
    10:10 am Management of CTCL Lauren Pinter Brown, MD, FACP
    10:25 am Comment Pier Luigi Porcu, MD
    10:30 am Audience Question and Answer All Faculty
    10:40 am Case-Based Discussion All Faculty
    11:00 am Post-Session Outcomes Survey  
    Chronic Myeloid Leukemia and Myeloproliferative Disorder Moderator: Dr. Harry Erba
    11:05 am Pre-session Outcomes Survey  
      Debate: First line treatment of CML: 2nd generation TKI or optimized Imatinib? Moderator: Harry Erba, MD, PhD
    11:10 am Imatinib Harry Erba, MD, PhD
    11:25 am 2nd Generation TKIs Michael Mauro, MD
    11:40 am Can therapy with TKIs ever be stopped? Should this be the primary goal of treatment? Moishe Talpaz, MD
    11:55 am Comment Michael Mauro, MD
    12:00 pm How to monitor patients receiving TKIs for CML Harry Erba, MD, PhD
    12:15 pm The management of accelerated and myeloid blast phase CML Richard Stone, MD
    12:30 pm Adjourn for Lunch  
    Chronic Myeloid Leukemia and Myeloproliferative Disorders (Continued)  
    1:45 pm Interferon Therapy for MPDs Richard Silver, MD
    2:00 pm All JAKed Up and No Place to Go - A Critical Evaluation of the Role of JAK2 Inhibitors Ruben Mesa, MD
    2:15 pm Audience Question & Answer All Faculty
    2:25 pm Case-Based Discussion All Faculty
    2:45 pm Post-Session Outcomes Survey  
    2:50 pm Break  
    Multiple Myeloma Moderator:  Sundar Jagannath, MD
    3:20 pm Pre-session Outcomes Survey  
    3:25 pm What Can We Learn From Multiple Myeloma Genomic Analysis? Nikhil Munshi, MD
    3:40 pm High Risk Smoldering Myeloma - Should We Intervene Early? Ola Landgren, PhD
    3:55 pm Current Trends: Treatment Strategies for Newly Diagnosed Elderly Patients with Myeloma James Berenson, MD
      Debate: HDT/ASCR for MM: Upfront v Relapse Moderator: Sundar Jagannath, MD
    4:10 pm Upfront James Berenson, MD
    4:25 pm Relapse Nikhil Munshi, MD
    4:40 pm Maintenance Therapy - Is It for Everyone? Nikhil Munshi, MD
    4:55 pm How To Best Use New Proteasome Inhibitors and IMiDs in Myeloma Sundar Jagganath, MD
    5:10 pm Audience Question & Answer All Faculty
    5:20 pm Case-Based Discussion All Faculty
    5:40 pm Post-Session Outcomes Survey  
    5:45 pm Adjourn  
         
    Saturday, February 16, 2013  
    7:00 am Breakfast  
    New Directions in Chronic Lymphocytic Leukemia Moderator: William Wierda, MD, PhD
    8:00 am Welcome and Pre-session Outcomes Survey  
    8:10 am Prognostic Factors: How To use in Clinical Practice William Wierda, MD, PhD
    8:25 am Treatment for Elderly CLL: Is There A Standard? Alessandra Ferrajoli, MD
    8:40 am Targeted Therapy for CLL: Focusing on the B Cell Receptor Pathway Jennifer Brown, MD, PhD
    8:55 am Targeting BCL-2 to Treat CLL Tom Kipps, MD, PhD
    9:10 am IMiDs and Combinations: How To Integrate into Standard Therapy Alessandra Ferrajoli, MD
    9:25 am Audience Question & Answer All Faculty
    9:35 am Cased-Based Discussion All Faculty
    9:55 am Post-Session Outcomes Survey  
    10:00 am Break  
    Acute Myeloid Leukemia and Myelodysplastic Syndrome Moderator: William Wierda, MD, PhD
    10:25 am Pre-session Outcomes Survey  
    10:30 am Can ‘pediatric’-like strategies be safely applied to adults with acute lymphocytic leukemia?  Daniel DeAngelo, MD, PhD
      Debate: Should patients with high risk MDS (and AML in early relapse) proceed directly to allogeneic transplantation without prior induction chemotherapy? William Wierda, MD, PhD
    10:45 am Yes Virginia Klemik, MD
    11:00 am No Harry Erba, MD, PhD
      Debate: Should older patients with AML be considered for lower intensity approaches rather than 3 & 7? Moderator: William Wierda, MD, PhD
    11:15 am Yes Richard Stone, MD
    11:30 am No Eric Feldman, MD, PhD
    11:45 am Is molecular characterization of cytogenetically normal AML helpful clinically? Ross Levine, MD
    12:00 pm The management of patients with MDS refractory to hypomethylating agents David Steensma, MD
    12:15 pm BiTES Daniel DeAngelo, MD, PhD
    12:30 pm Audience Question & Answer All Faculty
    12:40 pm Case-Based Discussion All Faculty
    12:55 pm Post-Session Outcomes Survey  
    1:00 pm Adjourn for Lunch  
    B Cell Lymphoma  
    2:15 pm Pre-session Outcomes Survey  
    2:20 pm Keynote: Epigenetics of Lymphoma Ari Melnik, MD
    2:50 pm How I Manage Early-Stage DLBCL Daniel Persky, MD
    3:05 pm Comment Craig Moskowitz, MD
    3:10 pm Advanced-Stage DLBCL Craig Moskowitz, MD
    3:20 pm Comment Andre Goy, MD
    3:25 pm Break  
    3:55 pm Relapsed DLBCL in the Rituximab Era Anas Younes, MD
    4:10 pm Comment Craig Moskowitz, MD
    4:15 pm New Directions in Follicular Lymphoma Bruce Cheson, MD
    4:30 pm Comment Andrew Zelenetz, MD, PhD
    4:35 pm Stem Cell Transplantation in Indolent Lymphoma Andre Goy, MD
    4:50 pm Comment Bruce Cheson, MD
    4:55 pm Audience Question and Answer All Faculty
    5:05 pm Post-Session Outcomes Survey  
    5:10 pm Adjourn  
         
    Sunday, February 17, 2013  
    7:00 am Breakfast  
    Supportive Care Moderator: Andrew Zelenetz, MD, PhD
    8:00 am Pre-session Outcomes Survey  
    8:05 am Management of Thrombocytopenia James Bussel, MD
    8:20 am Hepatitis B and Hematologic Malignancies Andrew Zelenetz, MD, PhD
    8:35 am Special Issues in Managing Hematologic Malignancies in the Adolescent and Young Adult Patrick Brown, MD
    8:50 am Adaptive Trial Design Using Surrogate Outcomes Don Berry, PhD
    9:05 am Audience Question and Answer  
    9:15 am Post-Session Outcomes Survey  
    Hodgkin Lymphoma Moderator: Andrew Zelenetz, MD, PhD
    9:20 am Pre-session Outcomes Survey  
    9:25 am The Life Cycle of a CLLB Cell Nicholas Chiorazzi, MD
    9:40 am Break  
      Debate: Should interim FDG-PET be used to guide therapy in HL? Moderator: Andrew Zelenetz, MD, PhD
    10:00 am Pro Craig Moskowitz, MD
    10:15 am Con Nancy Bartlett, MD
    10:30 am Management of HL in the Elderly Paul Hamlin, MD
    10:45 am Comment Nancy Bartlett, MD
      Debate: Localized Relapse in HL: Optimal Strategies Moderator: Andrew Zelenetz, MD, PhD
    10:50 am Transplant Craig Moskowitz, MD
    11:05 am New Field, Dose and Techniques in Radiotherapy of Lymphomas Joachim Yahalom, MD
    11:20 am Audience Question and Answer All Faculty
    11:30 am Case-Based Discussion All Faculty
    11:50 pm Post-Session Outcomes Survey  
    12:00 pm Adjourn for Lunch  
    12:00 - 1:15 pm Non- CME Lunch Symposium  or Lunch On Own  
         
    New Directions in Hematologic Malignancies Moderator: Andrew Zelenetz, MD, PhD
    1:15 pm Pre-session Outcomes Survey  
    1:30 pm ADC's in Lymphoma Andrew Zelenetz, MD, PhD
    1:45 pm Aurora Kinase Inhibition Johnathan Freidberg, MD
    2:00 pm Kinase Inhibitors in Lymphoma Jennifer Brown, MD, PhD
    2:15 pm Jak inihibtion in Lymhoma Anas Younes, MD
    2:30 pm IMIDS in Lymphoma Andre Goy, MD
    2:45 pm Audience Question and Answer All Faculty
    2:55 pm Post-Session Outcomes Survey  
    3:05 pm Closing Remarks Andrew Zelenetz, MD, PhD
    3:15 pm Conference Adjourn  

    Video sampling and photos from the 17th International Congress on Hematologic Malignancies®: Focus on Leukemias, Lymphomas and Myeloma (2013)


     


     
    Steven Horwitz, MD
    PER Pulse Recap: 17th International Congress on Hematologic Malignancies® – Multiple Myeloma

    The 17th Annual International Congress on Hematologic Malignancies® was held February 15-17, 2013, to discuss and debate the cutting-edge management of patients with leukemias, lymphomas, and myeloma. This PER Pulse Recap, the first of three presenting key topics from the International Congress on Hematologic Malignancies, is focused on new agents for the treatment of relapsed or refractory multiple myeloma.

    Dr. Sundar Jagannath presented information on the optimal use of novel proteasome inhibitors and immunomodulatory drugs (IMiDs) in multiple myeloma. The oral IMiD pomalidomide and the IV proteasome inhibitor carfilzomib are newly approved agents that have demonstrated activity in patients previously treated with drugs of the same class (ie, lenalidomide or thalidomide for patients receiving pomalidomide, and bortezomib for patients receiving carfilzomib). Pomalidomide and carfilzomib are each indicated for patients who have had at least two prior therapies (including an IMiD and bortezomib), whose disease has relapsed within 60 days of the last treatment. Both drugs are well tolerated, can be easily combined with other agents, and appear to extend survival in patients with relapsed/refractory myeloma.
    • What Can We Learn From Multiple Myeloma Genomic Analysis? - Nikhil Munshi, MD
    • High Risk Smoldering Myeloma—Should We Intervene Early?  - Ola Landgren, PhD
    • Current Trends: Treatment Strategies for Newly Diagnosed Elderly Patients With Myeloma  - James Berenson, MD
    • Debate: Role of Transplant in the Management of Multiple Myeloma - Nikhil Munshi, MD, and James Berenson, MD
    • Maintenance Therapy—Is It for Everyone?  - Nikhil Munshi, MD
    Click here to download PDF version


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