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Concluded -- 17th International Congress on Hematologic Malignancies®: Focus on Leukemias, Lymphomas and Myeloma (2013)

Overview
The 17th Annual International Congress on Hematologic Malignancies®: Focus on Leukemias, Lymphomas, and Myeloma will provide a unique opportunity for medical oncologists, hematologists, and other health care professionals to learn from and to interact with international leaders in the field of hematologic malignancies in order to increase knowledge, apply new data to practice, and improve patient outcomes.
Target Audience
This CME activity is directed toward medical oncologists and hematologists interested in the treatment of patients with hematologic malignancies. Fellows, nurse practitioners, nurses, physician assistants, pharmacists, researchers, and other health care professionals interested in the treatment of hematologic malignancies are also invited to participate.Learning Objectives
At the conclusion of this activity, you should be better prepared to:- Evaluate emerging clinical data regarding new agents and evolving strategies for the treatment of hematologic malignancies, and apply clinical trial data appropriately in order to optimize the outcome of individual patients
- Integrate genomic and molecular biomarkers when appropriate into risk assessment and treatment selection for patients with hematologic malignancies
- Compare efficacy and safety data supporting treatment options for lymphoma (including indolent and aggressive B cell lymphomas, Hodgkin lymphoma, and T cell lymphomas) in order to optimize outcomes for individual patients
- Individualize therapy for patient with newly diagnosed and relapsed/refractory multiple myeloma based on assessment of transplant eligibility, patient and tumor characteristics, and risk/benefit profiles of available regimens
- Discuss strategies for the first-line treatment of chronic-phase chronic myeloid leukemia, as well as monitoring guidelines and options for patients in accelerated- or blast-phase
- Evaluate the efficacy and safety of standard and emerging treatment approaches for patients with acute leukemias, myelodysplastic syndrome, and myeloproliferative disorders in order to personalize therapy for individual patients.
- Review recent advances in treatment options for chronic lymphocytic leukemia, including the use of prognostic factors, to optimize outcomes.
Disclosure Policy and Resolution of Conflicts of Interest (COI)
As a sponsor accredited by the Accreditation Council for Continuing Medical Education (ACCME), it is the policy of PER to ensure fair balance, independence, objectivity, and scientific rigor in all of its CME activities. PER additionally requires everyone who is in a position to control the content of a CME activity to disclose all relevant financial relationships with commercial interests. The ACCME defines “relevant financial relationships” as financial relationships in any amount occurring within the past 12 months that create a COI. All relevant financial relationships with any commercial interests are disclosed to participants prior to the beginning of PER’s CME activities. PER has identified and resolved all COI prior to the start of this activity using a multi-step process.Off-Label Disclosure and Disclaimer
This CME activity will contain discussions about off-label/unapproved uses of drugs including but not limited to brentuximab vedotin, carfilzomib, pomalidomide, doxorubicin, dexamethasone, bortezomib, bendamustine, melphalan, lenalidomide, delanzomib, ibrutinib, idelalisib, rituximab for ITP, romiplostim and eltrombopag for pediatric ITP, E5501 (avatrombopag maleate) for ITP, ABT‑199, IPI-145, SCDT 2980s, ofatumumab, aurora kinase inhibitors, GS-1101, PCYC-32765, IP2101, ibritumomab tiuxetan, interferon in MPNs, rigosertib, clofarabine for MDS, ponatinib, blinatumomab, azacitidine, decitabine and clofarbine.For additional information about approved uses, including approved indications, contraindications, and warnings, participants are advised to consult prescribing information for all products discussed or consult the Physicians’ Desk Reference. The information provided in this CME activity is for continuing medical education purposes only and is not meant to substitute for the independent medical judgment of a physician relative to diagnostic and treatment options for a specific patient’s medical condition.
Disclaimer
The opinions expressed in the content are solely those of the individual faculty members and do not reflect those of Physicians’ Education Resource®, LLC, or any of the companies that provided commercial support for this CME activity.
Chair
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Andrew D. Zelenetz, MD, PhD Memorial Sloan-Kettering Cancer Center New York, NY |
Program Committee
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Sundar Jagannath, MD The Tisch Cancer Institute Mount Sinai School of Medicine The Mount Sinai Medical Center New York, NY |
Charles Schiffer, MD Karmanos Cancer Institute Wayne State University School of Medicine Detroit, MI |
William G. Weirda, MD, PhD The University of Texas MD Anderson Cancer Center Houston, TX |
Faculty
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Ranjana Advani, MD Stanford Cancer Institute Stanford School of Medicine Stanford, CA Nancy Bartlett, MD Washington University School of Medicine St. Louis, MO James Berenson, MD Institute for Myeloma and Bone Cancer Research West Hollywood, CA Donald Berry, PhD University of Texas MD Anderson Cancer Center Houston, TX Jennifer Brown, MD, PhD Dana Farber Cancer Institute Harvard Medical School Boston, MA Patrick Brown, MD Sidney Kimmel Comprehensive Cancer Center Johns Hopkins University School of Medicine Baltimore, MD James Bussel, MD Weill Cornell Medical College New York, NY Bruce Cheson, MD Georgetown Lombardi Comprehensive Cancer Center Washington, DC Nicholas Chiorazzi, MD Weill Cornell Medical College New York, NY Daniel DeAngelo, MD, PhD Dana Farber Cancer Institute Boston, MA Harry Erba, MD University of Alabama Birmingham School of Medicine Birmingham, AL Eric Feldman, MD Weill Cornell Medical College New York, NY Alessandra Ferrajoli, MD University of Texas MD Anderson Cancer Center Houston, TX Jonathan Friedberg, MD, MMsc James P. Wilmont Cancer Center University of Rochester Medical Center Rochester, NY Randy Gascoyne, MD BC Cancer Agency Vancouver, BC, Canada Andre Goy, MD John Theurer Cancer Center at Hackensack University Medical Center Hackensack, NJ Paul Hamlin, MD Memorial Sloan Kettering Cancer Center New York, NY Steven Horwitz, MD Memorial Sloan Kettering Cancer Center New York, NY |
Virginia Klemik, MD Memorial Sloan Kettering Cancer Center New York, NY Thomas Kipps, MD, PhD UCSD Moores Cancer Center La Jolla, CA Ola Landgren, MD National Cancer Institute Bethesda, MD Ross Levine, MD Memorial Sloan Kettering Cancer Center New York, NY Michael Mauro, MD Oregon Health and Science University Portland, OR Ari Melnick, MD Weill Cornell Medical College New York, NY Ruben Mesa, MD, FACP Mayo Clinic Cancer Center Scottsdale, AZ Craig Moskowitz, MD Memorial Sloan Kettering Cancer Center New York, NY Nikhil Munshi, MD Dana Farber Cancer Institute Harvard Medical School Boston, MA Daniel O. Persky, MD Yale Cancer Center New Haven, CT Lauren Pinter-Brown, MD, FACP Geffen School of Medicine at UCLA Los Angeles, CA Pierluigi Porcu, MD The Ohio State University Comprehensive Cancer Center Arthur G. James Cancer Hospital Richard Solove Research Institute Columbus, OH Richard Silver, MD Weill Cornell Medical College New York, NY David Steensma, MD Dana Farber Cancer Center Harvard Medical School Boston, MA Richard Stone, MD Harvard Medical School Boston, MA Moshe Talpaz, MD University of Michigan Comprehensive Cancer Center Ann Arbor, MI Joachim Yahalom, MD Memorial Sloan Kettering Cancer Center New York, NY Anas Younes, MD The University of Texas MD Anderson Cancer Center Houston, TX |
Faculty and Staff Disclosures
The following individuals have relevant financial relationships with commercial interests to disclose:Ranjana Advani, MD – Grant/Research Support – Allos Therapeutics, Seattle Genetics; Nancy Bartlett, MD – Paid Travel Expenses (ASCO Poster Presentation) – Seattle Genetics; James Berenson, MD – Grant/Research Support – Amgen, Novartis, Medtronic, Onyx, Millennium; Consultant: Onyx, Millennium, Amgen, Medtronic; Speaker’s Bureau – Onyx, Millenium, Amgen, Medtronic; Donald Berry PhD – Consultant – Berry Consultants, LLC; Stock/Shareholder – Co-owner of Berry Consultants, LLC; Jennifer Brown, MD, PhD – Grant/Research Support – Genzyme (now sanofi-aventis); Consultant – Genentech, Emergent, sanofi-aventis, Celgene, Onyx; James Bussel, MD – Grant/Research Support – Amgen, Cangene, GlaxoSmithKline, Genzyme, IgG of America, Immunomedics, Ligand, Eisai Inc, Shionogi, Sysmex; Consultant/Ad Board – Amgen, GlaxoSmithKline, Ligand, Shionogi, Symphogen, Eisai, Inc; Stock/Shareholder – Amgen, GlaxoSmithKline; Bruce Cheson, MD – Consultant – Genentech, Celgene; Nicholas Chiorazzi, MD – Grant/Research Support: Pharmacyclics; Stock/Shareholder – Kinemed, Inc.; Daniel DeAngelo, MD, PhD – Consultant – Amgen; Harry Erba, MD – Grant/Research Support – Novartis, , Celator, GenzymeMillennium; Speaker’s Bureau – Celgene, Novartis, Incyte; Alessandra Ferrajoli, MD – Grant/Research Support – Celgene, GlaxoSmithKline; Other Support (Advisory Board) – Celgene, Pharmacyclics; Jonathan Friedberg, MD – Consultant – Genentech, Bayer, Seattle Genetics; Other Support (Data and Safety Monitoring): Lilly; Randy Gascoyne, MD, FRCPC – Grant/Research Support – Seattle Genetics, Roche Canada; Consultant – Seattle Genetics, Celgene, Janssen, Genentech, Roche; Speaker’s Bureau – Seattle Genetics; Andre Goy, MD – Clinical Trial Support Through Institutions; Speaker’s Bureau – Millennium; Advisory Board – Millennium, Celgene, Pharmacyclics, Johnson & Johnson, Seattle Genetics, Pfizer; Paul Hamlin, MD – Grant/Research Support – Spectrum, GlaxoSmithKline, Pfizer, Seattle Genetics; Consultant – Genentech, Gilead, Spectrum; Steven Horwitz, MD – Grant/Research Support – Celgene, Allos, Seattle Genetics, Infinity, Kyowa, Millennium; Consultant – Celgene, Allos, Seattle Genetics, Bristol Myers Squibb, Genzyme, Kyowa, Johnson & Johnson, Janssen, Millennium; Sundar Jagannath, MD – Consultant – Merck, Celgene, Millennium; Thomas Kipps, MD, PhD – Grant/Research Support – Abbott, Celgene, Genentech, Pharmacyclics, AstraZeneca, Amgen, Medimmude, Gilead; Consultant – Onyx; Stock/Shareholder – Eclipse Tx, Ingenica; Michael Mauro, MD – Grant/Research Support – Novartis, Bristol Myers Squibb, Ariad; Consultant – Novartis, Bristol Myers Squibb, Ariad, Pfizer; Ruben Mesa, MD, FACP – Research Support – Inyte, Celgene, Gilead, Infinity, Lilly, NS Pharma; Ari Melnick, MD – Grant/Research Support – NCI, Leukemia and Lymphoma Society; Consultant – Celgene; Speaker’s Bureau – Genentech; Craig Moskowitz, MD – Grant/Research Support – Seattle Genetics, Roche, GlaxoSmithKline, Plexxikon, Cephalon; Consultant – Seattle Genetics, Roche, GlaxoSmithKline; Nikhil Munshi, MD – Consultant – Celgene, Merck, Millenium, Onyx; Daniel Persky, MD – Grant/Research Support – Merck; Lauren Pinter-Brown, MD, FACP – Consultant – Spectrum; Pierluigi Porcu, MD – Grant/Research Support – Millennium; Consultant – Hospira, Elorac; Charles Schiffer, MD – Grant/Research Support – Ariad, Celgene, Ambit, Bristol Myers Squibb; Consultant – Eisai, Teva, Celgene, Novartis, Bristol Myers Squibb; Richard Silver, MD – Grant/Research Support – Merck; Clinical Trial Investigator – Interferon in treatment in early phase myleofibrosis; David Steensma, MD – Consultant – Amgen, Array, Biopharma, Boehringer Ingelheim, Celgene; Richard Stone, MD – Grant/Research Support – Novartis; Consultant – Teva, Seattle Genetics, Amgen; Other Support – Sunesis (OSMB), Amgen (Steering Committee); Moshe Talpaz, MD – Grant/Research Support – Novartis, Ariad, Bristol Myers Squibb, sanofi-aventis, Incyte; Consultant – Novartis, Ariad, Bristol Myers Squibb, Teva; Speaker’s Bureau – Novartis, Ariad; William Wierda, MD, PhD – Grant/Research Support – Abbott, GlaxoSmithKline, Genentech/Roche; Consultant – Celgene, Genentech/Roche, Merck, sanofi-aventis; Speaker’s Bureau – Celgene, GlaxoSmithKline, Genentech/Roche; Anas Younes, MD – Grant/Research Support – Seattle Genetics, Millennium, Johnson & Johnson, Gilead, Novartis; Consultant – Seattle Genetics, Millennium, ISIS, Novartis; Andrew Zelenetz, MD – Research – Roche, GlaxoSmithKline, Genentech; Consulting – Seattle Genetics, sanofi-aventis USA, GlaxoSmithKline, Gilead, Cephalon, Celgene; Other – Scientific Advisor – Cancer Genetics
The following individuals have no relevant financial relationships with commercial interests to disclose: Patrick Brown, MD; Eric Feldman, MD; Virginia Klimek, MD, Ola Landgren, MD, PhD; Ross Levine, MD; Joachim Yahalom, MD
Physicians’ Education Resource®, LLC Planning Staff – Ann C. Lichti, CCMEP, Tristan Nelsen, MNM, CMP and Susan Peck, PhD.
Off-Label Disclosure and Disclaimer
This CME activity will contain discussions about off-label/unapproved uses of drugs including but not limited to brentuximab vedotin, carfilzomib, pomalidomide, doxorubicin, dexamethasone, bortezomib, bendamustine, melphalan, lenalidomide, delanzomib, ibrutinib, idelalisib, rituximab for ITP, romiplostim and eltrombopag for pediatric ITP, E5501 (avatrombopag maleate) for ITP, ABT‑199, IPI-145, SCDT 2980s, ofatumumab, aurora kinase inhibitors, GS-1101, PCYC-32765, IP2101, ibritumomab tiuxetan, interferon in MPNs, rigosertib, clofarabine for MDS, ponatinib, blinatumomab, azacitidine, decitabine and clofarbine.
For additional information about approved uses, including approved indications, contraindications, and warnings, participants are advised to consult prescribing information for all products discussed or consult the Physicians’ Desk Reference. The information provided in this CME activity is for continuing medical education purposes only and is not meant to substitute for the independent medical judgment of a physician relative to diagnostic and treatment options for a specific patient’s medical condition.
Disclaimer
The opinions expressed in the content are solely those of the individual faculty members and do not reflect those of Physicians’ Education Resource®, LLC, or any of the companies that provided commercial support for this CME activity.
Agenda
Video sampling and photos from the 17th International Congress on Hematologic Malignancies®: Focus on Leukemias, Lymphomas and Myeloma (2013)














Steven Horwitz, MD















PER Pulse Recap: 17th International Congress on Hematologic Malignancies® – Multiple Myeloma
The 17th Annual International Congress on Hematologic Malignancies® was held February 15-17, 2013, to discuss and debate the cutting-edge management of patients with leukemias, lymphomas, and myeloma. This PER Pulse Recap, the first of three presenting key topics from the International Congress on Hematologic Malignancies, is focused on new agents for the treatment of relapsed or refractory multiple myeloma.
Dr. Sundar Jagannath presented information on the optimal use of novel proteasome inhibitors and immunomodulatory drugs (IMiDs) in multiple myeloma. The oral IMiD pomalidomide and the IV proteasome inhibitor carfilzomib are newly approved agents that have demonstrated activity in patients previously treated with drugs of the same class (ie, lenalidomide or thalidomide for patients receiving pomalidomide, and bortezomib for patients receiving carfilzomib). Pomalidomide and carfilzomib are each indicated for patients who have had at least two prior therapies (including an IMiD and bortezomib), whose disease has relapsed within 60 days of the last treatment. Both drugs are well tolerated, can be easily combined with other agents, and appear to extend survival in patients with relapsed/refractory myeloma.
The 17th Annual International Congress on Hematologic Malignancies® was held February 15-17, 2013, to discuss and debate the cutting-edge management of patients with leukemias, lymphomas, and myeloma. This PER Pulse Recap, the first of three presenting key topics from the International Congress on Hematologic Malignancies, is focused on new agents for the treatment of relapsed or refractory multiple myeloma.
Dr. Sundar Jagannath presented information on the optimal use of novel proteasome inhibitors and immunomodulatory drugs (IMiDs) in multiple myeloma. The oral IMiD pomalidomide and the IV proteasome inhibitor carfilzomib are newly approved agents that have demonstrated activity in patients previously treated with drugs of the same class (ie, lenalidomide or thalidomide for patients receiving pomalidomide, and bortezomib for patients receiving carfilzomib). Pomalidomide and carfilzomib are each indicated for patients who have had at least two prior therapies (including an IMiD and bortezomib), whose disease has relapsed within 60 days of the last treatment. Both drugs are well tolerated, can be easily combined with other agents, and appear to extend survival in patients with relapsed/refractory myeloma.
- What Can We Learn From Multiple Myeloma Genomic Analysis? - Nikhil Munshi, MD
- High Risk Smoldering Myeloma—Should We Intervene Early? - Ola Landgren, PhD
- Current Trends: Treatment Strategies for Newly Diagnosed Elderly Patients With Myeloma - James Berenson, MD
- Debate: Role of Transplant in the Management of Multiple Myeloma - Nikhil Munshi, MD, and James Berenson, MD
- Maintenance Therapy—Is It for Everyone? - Nikhil Munshi, MD
Contact PER
Physicians' Education Resource®, LLC
666 Plainsboro Rd. Suite 356
Plainsboro, NJ 08536
Phone (609) 378-3701
Fax (609) 257-0705
info@gotoper.com
Physicians' Education Resource®, LLC
666 Plainsboro Rd. Suite 356
Plainsboro, NJ 08536
Phone (609) 378-3701
Fax (609) 257-0705
info@gotoper.com



